An Egyptian court has sentenced Mohammed Badie, leader of the outlawed Muslim Brotherhood, and 13 other defendants to death for inciting violence.
Sentences handed down Saturday also included life imprisonment for a U.S.-Egyptian citizen, Mohammad Soltan, convicted of supporting the militant group.
The U.S. State Department said it was "deeply disappointed" by Soltan's sentence and was concerned about his health and detention. It called on Egypt to release him on humanitarian grounds.
The sentences can be appealed, a process that could take years.
The men are among the thousands detained after the ousting of Islamist President Mohamed Morsi in 2013.
Egypt has received international criticism for its mass trials of Muslim Brotherhood supporters.
Badie has also been charged with a number of other alleged crimes.