News / Health

Combination Pill Found Effective Against TB

4-in-1 tablet could reduce drug-resistance

A tuberculosis patient receives free treatment at the Indonesian Union Against Tuberculosis clinic in Jakarta, April 4, 2011.
A tuberculosis patient receives free treatment at the Indonesian Union Against Tuberculosis clinic in Jakarta, April 4, 2011.

Multimedia

Audio
TEXT SIZE - +
Art Chimes

A new study finds that combining four tuberculosis drugs into one pill could help fight drug-resistant strains of the disease.

One of the main reasons those strains develop is because many TB patients don't take their medicines as instructed. The World Health Organization's recommended treatment for tuberculosis includes four drugs. Combined in one pill, they are easier to take. But there have been doubts about whether the four-in-one pill is as effective.

In this new research, WHO scientist Christian Lienhardt and colleagues studied how patients responded to the combination pill compared with the drugs in separate pills. TB patients were recruited in 11 countries in Latin America, Africa, and Asia, and divided into two groups. One got the combination pill, the other took the same drugs in individual pills.

Lienhardt's team used three different methods to measure whether different ways of taking the drugs were equally effective. The found the combination pill was slightly less effective. But that might be more than compensated for by the assurance that the patient taking the combination pill is getting all the medicine, not a partial dose that could kill the weaker strains while allowing the more drug-resistant TB bugs to survive.

"It's important to be able to fight and prevent multi-drug resistance, which is really an emerging, and a very high concern for people who take care in the fight against tuberculosis," says Lienhardt. "And the best way to prevent resistance is to make sure that treatment is fully being taken."

The combination pills are already being used in some TB treatment programs, but other programs have avoided them because of concerns about their effectiveness compared with individual pills.

The study was funded by the U.S. Agency for International Development (USAID) which, the authors say, had no role in the conduct of the study or its conclusions.

The paper by Christian Lienhardt of the World Health Organization and his colleagues is published in the Journal of the American Medical Association, JAMA.  

You May Like

Photogallery Pope's Easter Prayer: Peace in Ukraine, Syria

Pontiff also calls for end to terrorist acts in Nigeria, violence in Iraq, and success in peace talks between Israelis and Palestinians More

Abdullah Holds Lead in Afghan Presidential Election

Country's Election Commission says that with half of the ballots counted, former FM remains in the lead with 44 percent of the vote More

Russia-Ukraine Crisis Could Trigger Cyber War

As tensions between Kyiv and Moscow escalate, so too has frequency of online attacks targeting government, news and financial sites More

This forum has been closed.
Comments
     
There are no comments in this forum. Be first and add one

Featured Videos

Your JavaScript is turned off or you have an old version of Adobe's Flash Player. Get the latest Flash player.
Ukraine, Russia, United in Faith, Divided in Politicsi
X
Michael Eckels
April 19, 2014
There is a strong historical religious connection between Russia and Ukraine. But what role is religion playing in the current conflict? In the run-up to Easter, Michael Eckels in Moscow reports for VOA.
Video

Video Ukraine, Russia, United in Faith, Divided in Politics

There is a strong historical religious connection between Russia and Ukraine. But what role is religion playing in the current conflict? In the run-up to Easter, Michael Eckels in Moscow reports for VOA.
Video

Video Face of American Farmer is Changing

The average American farmer is now 58 years old, and farmers 65 and older are the fastest growing segment of the population. It’s a troubling trend signaling big changes ahead for American agriculture as aging farmers retire. Reporter Mike Osborne says a new report from the U.S. Census Bureau is suggesting what some of those changes might look like... and why they might not be so troubling.
Video

Video Donetsk Governor: Ukraine Military Assault 'Delicate But Necessary'

Around a dozen state buildings in eastern Ukraine remain in the hands of pro-Russian protesters who are demanding a referendum on self-rule. The governor of the whole Donetsk region is among those forced out by the protesters. He spoke to VOA's Henry Ridgwell from his temporary new office in Donetsk city.
Video

Video Drones May Soon Send Data From High Seas

Drones are usually associated with unmanned flying vehicles, but autonomous watercraft are also becoming useful tools for jobs ranging from scientific exploration to law enforcement to searching for a missing airliner in the Indian Ocean. VOA’s George Putic reports on sea-faring drones.
Video

Video New Earth-Size Planet Found

Not too big, not too small. Not too hot, not too cold. A newly discovered planet looks just right for life as we know it, according to an international group of astronomers. VOA’s Steve Baragona has more.
Video

Video Copts in Diaspora Worry About Future in Egypt

Around 10 percent of Egypt’s population belong to the Coptic faith, making them the largest Christian minority in the Middle East. But they have become targets of violence since the revolution three years ago. With elections scheduled for May and the struggle between the Egyptian military and Islamists continuing, many Copts abroad are deeply worried about the future of their ancient church. VOA religion correspondent Jerome Socolovsky visited a Coptic church outside Washington DC.
Video

Video Critics Say Venezuelan Protests Test Limits of Military's Support

During the two months of deadly anti-government protests that have rocked the oil-rich nation of Venezuela, President Nicolas Maduro has accused the opposition of trying to initiate a coup. Though a small number of military officers have been arrested for allegedly plotting against the government, VOA’s Brian Padden reports the leadership of the armed forces continues to support the president, at least for now.
Video

Video More Millenials Unplug to Embrace Board Games

A big new trend in the U.S. toy industry has more consumers switching off their high-tech gadgets to play with classic toys, like board games. This is especially true among the so-called millenial generation - those born in the 1980's and 90's. Elizabeth Lee has more from an unusual café in Los Angeles, where the new trend is popular and business is booming.
Video

Video Google Buys Drone Company

In its latest purchase of high-tech companies, Google has acquired a manufacturer of solar-powered drones that can stay in the air almost indefinitely, relaying broadband Internet connection to remote areas. It is seen as yet another step in the U.S. based Web giant’s bid to bring Internet to the whole world. VOA’s George Putic reports.
AppleAndroid