News / Health

Inherited Vulnerability to Drug Addiction Discovered

Brain abnormalities found in addicts and their non-addicted siblings

Brain abnormalities found in addicts and their non-addicted siblings suggest these congenital differences might be to blame for the increased vulnerability to drug abuse.
Brain abnormalities found in addicts and their non-addicted siblings suggest these congenital differences might be to blame for the increased vulnerability to drug abuse.

Multimedia

Audio
Jessica Berman

Scientists have discovered structural abnormalities in the brains of drug addicts and their non-addicted siblings, a finding that suggests there may be an inherited vulnerability to addiction, and that behavioral therapies could help addicts recover.  

Substance abuse is known to run in families, according to experts, who say that having an addicted family member increases a person’s risk of addiction by eight to ten percent above the general population.  



Researchers have yet to identify an addiction gene. But Karen Esche at the University of Cambridge in Britain says the brain abnormalities found in addicts and their non-addicted siblings suggest these congenital differences might be to blame for the increased vulnerability to drug abuse.  

“This may suggest that some of the impairments that we see in the drug users are not caused by the drugs or [do not] predispose them to addiction,” Esche says.

Esche's team used magnetic resonance imaging to take pictures of the brains of cocaine addicts and their non-addicted siblings. The images showed the same patterns of abnormalities in the pre-frontal and striatal regions of the brain, patterns not evident in the brains of unrelated volunteers.

Researchers also tested the study participants to see how quickly they could switch from one task to another. The addicted sibling pairs fared much worse than the volunteers, suggesting high levels of impulsivity and a lack of self-control.

“Which again puts them at risk of taking drugs, because what we see in addiction is that that self-control gets lost," Esche says. "Loss of control - loss of control over drug use - is a hallmark of addiction.”

Nora Volkow, director of the U.S. National Institute on Drug Abuse, says the study suggests the brain abnormalities observed in the addicted sibling are not due to chronic and repeated drug abuse. She believes people with a biological vulnerability to drug abuse can resist the temptation, which is good news for drug addicts.

“Even if you have a vulnerability in your brain that makes those areas not function properly, you can overcome it by interventions that can help you strengthen it,” she says.

According to Volkow, aerobic exercise has been shown to improve impulse control. So, too, have computer training programs designed to strengthen the pre-frontal areas of the brain that have been implicated in addiction.

You May Like

In US, Still No Decision in Racially-charged Case

Missouri town, many Americans on edge over whether jurors will indict white police officer in August shooting death of unarmed black teen More

Corruption Fighters Want More From World’s Strongest Nations

Anti-corruption activists say final communique fell short of expectations and failed to fully address systemic problems More

Philippines Leery of Development on Reef Reclamation in S. China Sea

Chinese land reclamation projects in area have been ongoing for years, but new satellite imagery reportedly shows China’s massive construction project More

This forum has been closed.
Comments
     
There are no comments in this forum. Be first and add one

Featured Videos

Your JavaScript is turned off or you have an old version of Adobe's Flash Player. Get the latest Flash player.
Ukraine Marks Anniversary of Deadly 1930s Faminei
X
Daniel Schearf
November 23, 2014 4:32 PM
During a commemoration for millions who died of starvation in Ukraine in the early 1930s, President Petro Poroshenko lashed out at Soviet-era totalitarianism for causing the deaths and accused today’s Russian-backed rebels in the east of using similar tactics. VOA’s Daniel Shearf reports from Kyiv.
Video

Video Ukraine Marks Anniversary of Deadly 1930s Famine

During a commemoration for millions who died of starvation in Ukraine in the early 1930s, President Petro Poroshenko lashed out at Soviet-era totalitarianism for causing the deaths and accused today’s Russian-backed rebels in the east of using similar tactics. VOA’s Daniel Shearf reports from Kyiv.
Video

Video Hong Kong Protests at a Crossroads

New public opinion polls in Hong Kong indicate declining support for pro-democracy demonstrations after weeks of street protests. VOA’s Bill Ide in Guangzhou and Pros Laput in Hong Kong spoke with protesters and observers about whether demonstrators have been too aggressive in pushing for change.
Video

Video Law Enforcement, Activists in Ferguson Agree to Keep Peace

Authorities in Ferguson, Missouri, say they have agreed with protest leaders to maintain peace when a grand jury reaches its decision on whether to indict a white police officer in the shooting death of a black teenager. Ferguson, a suburb of St. Louis, has been the scene of intermittent violence since the August 9 shooting intensified long-simmering antagonism between the police and the African-American community. VOA's Zlatica Hoke reports.
Video

Video US Immigration Relief Imminent for Mixed-Status Families

Tens of thousands of undocumented immigrants in the Washington, D.C., area may benefit from a controversial presidential order announced this week. It's not a path to citizenship, as some activists hoped. But it will allow more immigrants who arrived as children or who have citizen children, to avoid deportation and work legally. VOA's Victoria Macchi talks with one young man who benefited from an earlier presidential order, and whose parents may now benefit after years of living in fear.
Video

Video New Skateboard Defies Gravity

A futuristic dream only a couple of decades ago, the hoverboard – a skateboard that floats above the ground - has finally been made possible. While still not ready for mass production, it promises to become a cool mode of transport... at least over some surfaces. VOA’s George Putic reports.
Video

Video Falling Gas Prices Impact US Oil Extraction

With the price of oil now less than $80 a barrel, motorists throughout the United States are benefiting from gas prices below $3 a gallon. But as VOA’s Kane Farabaugh reports, the decreasing price of petroleum has a downside for the hydraulic fracturing industry in the United States.
Video

Video Tensions Build on Korean Peninsula Amid Military Drills

It has been another tense week on the Korean peninsula as Pyongyang threatened to again test nuclear weapons while the U.S. and South Korean forces held joint military exercises in a show of force. VOA’s Brian Padden reports from the Kunsan Air Base in South Korea.
Video

Video Mama Sarah Obama Honored at UN Women’s Entrepreneurship Day

President Barack Obama's step-grandmother is in the United States to raise money to build a $12 million school and hospital center in Kogelo, Kenya, the birthplace of the president's father, Barack Obama, Sr. She was honored for her decades of work to aid poor Kenyans at a Women's Entrepreneurship Day at the United Nations.
Video

Video Gay Evangelicals Argue That Bible Does Not Condemn Homosexuality

More than 30 U.S. states now recognize same-sex marriages, and an increasing number of mainline American churches are blessing them. But evangelical church members- which account for around 30 percent of the U.S. adult population - believe the Bible unequivocally condemns homosexuality. VOA's Jerome Socolovsky reports that gay, lesbian, bisexual and transgender evangelicals are coming out. Backed by a prominent evangelical scholar, they argue that the traditional reading of the bible is wrong.
Video

Video Ebola Economic Toll Stirs W. Africa Food Security Concerns

The World Bank said Wednesday that it expects the economic impact of the Ebola outbreak on the sub-Saharan economy to cost somewhere betweenf $3 billion to $4 billion - well below a previously-outlined worst-case scenario of $32 billion. Some economists, however, paint a gloomier picture - warning that the disruption to regional markets and trading is considerable. Henry Ridgwell reports from London.
Video

Video Chaos, Abuse Defy Solution in Libya

The political and security crisis in Libya is deepening, with competing governments and, according to Amnesty International, widespread human rights violations committed with impunity. VOA’s Al Pessin reports from London.
Video

Video US Hosts Record 866,000 Foreign Students

Close to 900,000 international students are studying at American universities and colleges, more than ever before. About half of them come from Asia, mostly China. The United States hosts more foreign students than any other country in the world, and its foreign student population is steadily growing. Zlatica Hoke reports.

All About America

AppleAndroid