News / Health

    Polio Vaccine Protects with Just One-Fifth Usual Dose

    Child receiving polio vaccine
    Child receiving polio vaccine

    Multimedia

    Audio
    Art Chimes

    Efforts to eradicate polio have been frustrated by a variety of factors, and unlike smallpox, the disease has defied long-running and expensive efforts to wipe it out. Now, a new study indicates that one of several polio vaccines can be effective at one-fifth the dose, cutting vaccination costs dramatically.

    There are several different kinds of polio vaccine. The oral vaccine – made with a weakened, live virus – has been used extensively in polio eradication efforts. World Health Organization polio official Roland Sutter says it's cheap and easy to use, "But it has one major side effect," he said. "It can rarely, very rarely, cause what we call vaccine-induced paralytic polio myelitis."

    That's the very disease the vaccine is intended to prevent. So in countries where polio has already been eradicated, the vaccine of choice uses a killed form of the polio virus. But Sutter says that vaccine has a different problem - its cost.

    "The inactivated polio virus vaccine, IPV, is currently quite expensive. The cheapest way we possibly can get it now is about $3 a dose. And so, this compares to 15 cents for the oral polio virus vaccine."

    There are several ways to bring down the price per dose. Manufacturing can be moved to developing countries, where costs are lower. The production process can be made more efficient. Extra ingredients, called adjuvants, can be added to the vaccine to make it more effective. Those are all on the table, but maybe the easiest way to cut the cost of vaccination is to reduce the amount of vaccine.

    That's the subject of new research by Roland Sutter and colleagues from public health institutes in the U.S. and the Netherlands, and the Ministry of Health in Oman.

    In their study, one group of children in Oman was vaccinated with the usual dose of the inactivated polio vaccine, while another group was vaccinated using only one-fifth the usual amount.

    The ones who got the smaller dose were fully protected, even though the vaccine prompted production of fewer antibodies than with the full dose.

    "So these lower levels are actually still quite good and will protect the child from polio," he said.

    But Sutter cautions that reducing the amount of vaccine used by 80 percent doesn't lower the cost of vaccination by 80 percent. The actual vaccine amounts to only one-third or less of the cost of a vaccination program. But still, he says, it's a "huge step forward" in the ongoing battle against a crippling disease.

    Sutter and his colleagues describe their research in the New England Journal of Medicine.

    You May Like

    Former US Envoys Urge Obama to Delay Troop Cuts in Afghanistan

    Keeping troop levels up during conflict with both Taliban and Islamic State is necessary to support Kabul government, they say

    First Lady to Visit Africa to Promote Girls' Education

    Michele Obama will be joined by daughters and actresses Meryl Streep and Freida Pinto

    Video NYSE Analyst: Brexit Will Continue to Place Pressure on Markets

    Despite orderly pricing and execution strategy at the New York Stock Exchange, analyst explains added pressure on world financial markets is likely

    This forum has been closed.
    Comments
         
    There are no comments in this forum. Be first and add one

    Featured Videos

    Your JavaScript is turned off or you have an old version of Adobe's Flash Player. Get the latest Flash player.
    Brexit Vote Plunges Global Markets Into Uncharted Territoryi
    X
    June 24, 2016 9:38 PM
    British voters plunged global markets into unknown territory after they voted Thursday to leave the European Union. The results of the Brexit vote, the term coined to describe the referendum, caught many off guard. Analysts say the resulting volatility could last for weeks, perhaps longer. Mil Arcega reports.
    Video

    Video Brexit Vote Plunges Global Markets Into Uncharted Territory

    British voters plunged global markets into unknown territory after they voted Thursday to leave the European Union. The results of the Brexit vote, the term coined to describe the referendum, caught many off guard. Analysts say the resulting volatility could last for weeks, perhaps longer. Mil Arcega reports.
    Video

    Video Orlando Shooting Changes Debate on Gun Control

    It’s been nearly two weeks since the largest mass shooting ever in the United States. Despite public calls for tighter gun control laws, Congress is at an impasse. Democratic lawmakers resorted to a 1960s civil rights tactic to portray their frustration. VOA’s Carolyn Presutti explains how the Orlando, Florida shooting is changing the debate.
    Video

    Video Tunisian Fishing Town Searches for Jobs, Local Development Solutions

    As the European Union tries to come to grips with its migrant crisis, some newcomers are leaving voluntarily. But those returning to their home countries face an uncertain future.  Five years after Tunisia's revolution, the tiny North African country is struggling with unrest, soaring unemployment and plummeting growth. From the southern Tunisian fishing town of Zarzis, Lisa Bryant takes a look for VOA at a search for local solutions.
    Video

    Video 'American Troops' in Russia Despite Tensions

    Historic battle re-enactment is a niche hobby with a fair number of adherents in Russia where past military victories are played-up by the Kremlin as a show of national strength. But, one group of World War II re-enactors in Moscow has the rare distinction of choosing to play western ally troops. VOA's Daniel Schearf explains.
    Video

    Video Experts: Very Few Killed in US Gun Violence Are Victims of Mass Shootings

    The deadly shooting at a Florida nightclub has reignited the debate in the U.S. over gun control. Although Congress doesn't provide government health agencies funds to study gun violence, public health experts say private research has helped them learn some things about the issue. VOA's Carol Pearson reports.
    Video

    Video Trump Unleashes Broadside Against Clinton to Try to Ease GOP Doubts

    Recent public opinion polls show Republican Donald Trump slipping behind Democrat Hillary Clinton in the presidential election matchup for November. Trump trails her both in fundraising and campaign organization, but he's intensifying his attacks on the former secretary of state. VOA National Correspondent Jim Malone reports.
    Video

    Video Muslim American Mayor Calls for Tolerance

    Syrian-born Mohamed Khairullah describes himself as "an American mayor who happens to be Muslim." As the three-term mayor of Prospect Park, New Jersey, he believes his town of 6,000 is an example of how ethnicity and religious beliefs should not determine a community's leadership. Ramon Taylor has this report from Prospect Park.
    Video

    Video Internal Rifts Over Syria Policy Could Be Headache for Next US President

    With the Obama administration showing little outward enthusiasm for adopting a more robust Syria policy, there is a strong likelihood that the internal discontent expressed by State Department employees will roll over to the next administration. VOA State Department correspondent Pam Dockins reports.
    Video

    Video Senegal to Park Colorful ‘Cars Rapide’ Permanently

    Brightly painted cars rapide are a hallmark of Dakar, offering residents a cheap way to get around the capital city since 1976. But the privately owned minibuses are scheduled to be parked for good in late 2018, as Ricci Shryock reports for VOA.
    Video

    Video Florida Gets $1 Million in Emergency Government Funding for Orlando

    The U.S. government has granted $1 million in emergency funding to the state of Florida to cover the costs linked to the June 12 massacre in Orlando. U.S. Attorney General Loretta Lynch announced the grant Tuesday in Orlando, where she met with survivors of the shooting attack that killed 49 people. Zlatica Hoke reports.
    Video

    Video How to Print Impossible Shapes with Metal

    3-D printing with metals is rapidly becoming more advanced. As printers become more affordable, the industry is partnering with universities to refine processes for manufacturing previously impossible things. A new 3-D printing lab aims to bring the new technology closer to everyday use. VOA's George Putic reports.
    Video

    Video Big Somali Community in Minnesota Observes Muslim Religious Feast

    Ramadan is widely observed in the north central US state of Minnesota, which a large Muslim community calls home. VOA Somali service reporter Mohmud Masadde files this report from Minneapolis, the state's biggest city.

    Special Report

    Adrift The Invisible African Diaspora