News / Health

Stem Cell Treatment Boosts Heart Function

Study notes 'striking' improvement in heart failure patients

The heart's ability to pump blood improved after  patients were injected with adult stem cells taken from their own hearts, according to a study led by Dr. Roberto Bolli of the University of Louisville.
The heart's ability to pump blood improved after patients were injected with adult stem cells taken from their own hearts, according to a study led by Dr. Roberto Bolli of the University of Louisville.

Multimedia

Audio
Art Chimes

A stem cell treatment for patients with heart failure significantly improved their heart function in a small but promising new study.

In heart failure, the heart loses its ability to efficiently pump blood. It is most often caused by a heart attack, which destroys some of the muscle tissue essential to a normal heartbeat.

In this new study, patients were injected with adult stem cells taken from their own hearts. These are a special kind of undifferentiated cell found throughout the body that helps to maintain and repair the tissue in which they are found.



Doctors use a measure called 'ejection fraction' to describe the heart's ability to pump blood. Study author Dr. Roberto Bolli of the University of Louisville says people in the control group showed no significant improvement in that measure. But he called the improvement in the stem cell patients "striking."

"At four months, the pumping ability of the heart was markedly improved," he reports. "The ejection fraction increased by eight points at four months, and at one year it increased by 12 points. Now, this is a huge increase, much greater than what we even hoped for when we started our study."

And Bolli says there was a significant improvement in the ability of the stem cell recipients to exercise.

The study participants also got MRI scans before and after treatment. A year after getting the stem cells, the images showed a 30 percent reduction in the scars of dead heart muscle.

"The reduction of the scar implies that new heart muscle is being produced to replace that scar. And so it is evidence that the stem cells are regenerating new heart muscle."

This ongoing study is very small, with just 16 patients in the stem cells group, plus seven more in the control group. But a commentary published with his paper says Bolli's findings "raise new optimism" because of the study's rigorous quality and unexpectedly good results.

Bolli published his findings in The Lancet and presented them at the American Heart Association meeting in Florida.

Also at that Heart Association meeting: another report of stem cell research, though with less promising results. In a study published in the journal of the American Medical Association, JAMA, researchers gave recent heart attack victims stem cells taken from their bone marrow. The idea was to prevent the onset of heart failure. Earlier studies had suggested the technique might work. But in this case, after six months there was no improvement in heart function.

You May Like

Missouri Town Braces for Possible Racial Unrest

Situation in Ferguson hinges on whether white police officer will be indicted for August shooting death of unarmed black teen; decision could come Monday More

Video Ukraine Marks Anniversary of 1930s Deadly Famine

President Poroshenko compares Soviet-era ‘genocide’ to current tactics of pro-Russia rebels in Ukraine's east More

S. Philippines Convictions Elusive 5 Years After Election-related Killings

Officials vowed to deliver justice as the nation marked the anniversary of the country's worst political massacre that left 58 dead, more than half media More

This forum has been closed.
Comments
     
There are no comments in this forum. Be first and add one

Featured Videos

Your JavaScript is turned off or you have an old version of Adobe's Flash Player. Get the latest Flash player.
New Skateboard Defies Gravityi
X
November 21, 2014 5:07 AM
A futuristic dream only a couple of decades ago, the hoverboard – a skateboard that floats above the ground - has finally been made possible. While still not ready for mass production, it promises to become a cool mode of transport... at least over some surfaces. VOA’s George Putic reports.
Video

Video New Skateboard Defies Gravity

A futuristic dream only a couple of decades ago, the hoverboard – a skateboard that floats above the ground - has finally been made possible. While still not ready for mass production, it promises to become a cool mode of transport... at least over some surfaces. VOA’s George Putic reports.
Video

Video Falling Gas Prices Impact US Oil Extraction

With the price of oil now less than $80 a barrel, motorists throughout the United States are benefiting from gas prices below $3 a gallon. But as VOA’s Kane Farabaugh reports, the decreasing price of petroleum has a downside for the hydraulic fracturing industry in the United States.
Video

Video Tensions Build on Korean Peninsula Amid Military Drills

It has been another tense week on the Korean peninsula as Pyongyang threatened to again test nuclear weapons while the U.S. and South Korean forces held joint military exercises in a show of force. VOA’s Brian Padden reports from the Kunsan Air Base in South Korea.
Video

Video Mama Sarah Obama Honored at UN Women’s Entrepreneurship Day

President Barack Obama's step-grandmother is in the United States to raise money to build a $12 million school and hospital center in Kogelo, Kenya, the birthplace of the president's father, Barack Obama, Sr. She was honored for her decades of work to aid poor Kenyans at a Women's Entrepreneurship Day at the United Nations.
Video

Video Gay Evangelicals Argue That Bible Does Not Condemn Homosexuality

More than 30 U.S. states now recognize same-sex marriages, and an increasing number of mainline American churches are blessing them. But evangelical church members- which account for around 30 percent of the U.S. adult population - believe the Bible unequivocally condemns homosexuality. VOA's Jerome Socolovsky reports that gay, lesbian, bisexual and transgender evangelicals are coming out. Backed by a prominent evangelical scholar, they argue that the traditional reading of the bible is wrong.
Video

Video Ebola Economic Toll Stirs W. Africa Food Security Concerns

The World Bank said Wednesday that it expects the economic impact of the Ebola outbreak on the sub-Saharan economy to cost somewhere betweenf $3 billion to $4 billion - well below a previously-outlined worst-case scenario of $32 billion. Some economists, however, paint a gloomier picture - warning that the disruption to regional markets and trading is considerable. Henry Ridgwell reports from London.
Video

Video Mexico Protests Escalate Over Disappearances

Protests in Mexico over 43 students missing since September continue to escalate, reflecting growing anger among Mexicans about a political system they view as corrupt, and increasingly tainted by the drug trade. Mounting outrage over the disappearances is now focused on the government of President Enrique Pena Nieto, accused of not doing enough to end insecurity in the country. More from VOA's Victoria Macchi.
Video

Video US Senate Votes Down Controversial Oil Pipeline - For Now

The U.S. Senate has rejected construction of a controversial pipeline to transport Canadian oil to American refineries. The $5 billion project still could be approved next year, but it faces a possible veto by President Barack Obama. As VOA’s Michael Bowman reports, the pipeline has exposed deep divisions in Congress about America’s energy future.
Video

Video Can Minsk Cease-fire Agreement Hold?

Growing tensions between government troops and separatists in eastern Ukraine further threaten a cease-fire agreement reached two months ago in the Belarusian capital of Minsk. Critics of U.S. policy in Ukraine say it is time the Obama administration gives up on that much-violated cease-fire and moves toward a new deal with Russia. VOA's Scott Stearns has more.
Video

Video Chaos, Abuse Defy Solution in Libya

The political and security crisis in Libya is deepening, with competing governments and, according to Amnesty International, widespread human rights violations committed with impunity. VOA’s Al Pessin reports from London.
Video

Video US Hosts Record 866,000 Foreign Students

Close to 900,000 international students are studying at American universities and colleges, more than ever before. About half of them come from Asia, mostly China. The United States hosts more foreign students than any other country in the world, and its foreign student population is steadily growing. Zlatica Hoke reports.
Video

Video Ferguson Church Grapples with Race Relations

Many white residents of Ferguson, Missouri, say they chose to live there because of the American Midwest community's diversity. So, they were shocked when a white police officer killed an unarmed black teenager in August – and shaken by the resulting protests and violence. Some local churches are leading conversations on how to go forward. VOA’s Ayesha Tanzeem reports.

All About America

AppleAndroid