A new
study has found that a fat cell gene may reduce the risk of colon cancer in
some people. The study provides what scientists say is the first evidence of a
genetic link between a fat cell gene and colon cancer. The research could lead
to better tests for the disease as well as measures to help prevent it.
A doctor in Plano, Texas, performs a colonoscopy on a patient
Current evidence suggests a relationship
between obesity, insulin resistance and colon cancer risk. The scientists say
what they have found now is an area of a gene that is connected with the cancer
risk. They say this area is most likely not the cause of the disease, but they
think it is where the connection comes from.
The gene
is involved in the formation of a hormone called adiponectin. Some people have
higher levels of this hormone in their blood, others have lower levels. Higher
levels have been linked with lower rates of obesity and insulin resistance. And
lower levels have been linked with higher rates.
The
Journal of the American Medical Association published the new findings last
week. Boris Pasche from the Comprehensive Cancer Center at the University of
Alabama at Birmingham led the research.
Colon
cancer is one of the leading causes of cancer deaths. Every year it kills
almost six hundred eighty thousand people around the world. And doctors find
more than one million new cases. The disease is highly treatable if discovered
early.
The
research involved two studies with a total of about one thousand five hundred
people. The larger of the two studies involved New Yorkers of Ashkenazi Jewish
ancestry. Colon cancer is more common in Jews of eastern European ancestry than
in the general population. The other study involved people of different
ethnicities from Chicago, Illinois.
Currently,
in the United States, the general advice is for colonoscopy tests for colon
cancer to begin at the age of fifty. A colonoscopy can find and remove growths
before they become cancerous. But the test is invasive and can be
uncomfortable.
A study
last month in the New England Journal of Medicine expressed support for a test
called a virtual colonoscopy. It uses X-ray and computer technology to search
for growths, but cannot remove them. There are still some questions about the
effectiveness of a virtual colonoscopy compared to a traditional one. But
doctors hope it might appeal to people who would otherwise not be tested at
all.
And
that's the VOA Special English Health Report, written by Caty Weaver. I'm Steve
Ember.