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Experts Urge Limits on Widely Used Pain Drug

07 July 2009

This is the VOA Special English Health Report.

The United States government might place new restrictions on a commonly used painkiller. Taking too much acetaminophen can cause liver damage and even death.

Last week, a group of experts advised the Food and Drug Administration that the drug needs more controls and better directions for use.  Acetaminophen, also called paracetamol, is found in Tylenol, Excedrin and other products that do not require a doctor's prescription. These products are used for pain, fever, colds and sleeplessness.

Their easy availability is part of the problem. People can accidentally take too much acetaminophen if they take several medicines that all contain it.

Tylenol is one of the most popular painkillers containing acetaminophen
Tylenol is one of the most popular painkillers containing acetaminophen
The experts recommended reducing the largest non-prescription dose of acetaminophen from one thousand milligrams. They said that is too much. They said adults should not take more than six hundred fifty milligrams at a time. The experts also said people should take less than four thousand milligrams of acetaminophen in a single day.

Acetaminophen overdose is a leading cause of liver damage in the United States. Researchers say it resulted in fifty-six thousand emergency room visits a year during the nineteen nineties. There were almost four hundred sixty deaths a year from liver failure.

The committee was especially concerned about prescription drugs that combine acetaminophen with stronger painkillers. The experts recommended banning combination drugs like Percocet and Vicodin.

Still, the experts were divided in their votes. The agency is not required to follow the advice of its committees, but generally does.

Acetaminophen is valued as a pain and fever reducer for adults and children. It does not cause stomach problems or bleeding like aspirin, ibuprofen and some other competing drugs can.

But experts say taking even small amounts over the recommended dose can cause liver damage. Some people suffer harm from smaller amounts than others. Alcohol use with acetaminophen is especially bad for the liver.

Signs of liver injury include nausea, vomiting and a lack of energy. But these may not develop for two or three days after an overdose -- too late to prevent damage.

People should ask a health professional about drug combinations that could be harmful. And they should make sure they know what is in the medicines they take and how much of each drug is safe to take.

And that's the VOA Special English Health Report, written by Mario Ritter. I'm Steve Ember.



Comments:

1. Health

It´s interesting. We usualy take paracetamol like water. People don´t know that paracetamol is harmful for liver. Mother gives their children paracetamol without medical prescription
Submitted by: Luis (Spain)
07-13-2009 - 19:08:45

2. Intresting to learn English

Please give some advoice how to learn english and what's important in english learning means grammer Vocablary or some thing els, thanks
Submitted by: Zubair (Afghanistan)
07-13-2009 - 05:38:56

3. Recommedation:

Hi to all. It's necessary for us as a consumer of the drugs to be aware of drug combinations, that is what is in the medicines or drugs we have to take whether it is prescriptive or non-prescriptive as well as their recommended doses , I mean how much each drug is safe to take.If we follow these recommended instructions tagged on them, it would not be hazardous for us to take them in a short period of time.I wanna recommend those who read my comments NOT to allow everything exceeds it's limits. For example, taking painkiller must not continue for a long time but we should stop it when we feel better or get better,I mean we should set a limit on everything.This Tajik from IRAN.Thank VOA programe.
Submitted by: Ali Akbar Tajik (Iran_Varamin)
07-11-2009 - 10:55:59

4. Period Pain

Agreed.. If it aint broke, dont fix it. Just be more forthcomming on the risk of overdose. I have bad periods and need these meds both over the couter and prescription. at different levels of course when pain is bad and unbarrable.. LEAVE it all alone people
Submitted by: Beth (USA)
07-10-2009 - 02:25:47

5. international problem

Unfortunately using painkillers are also increased rapidly in Iran. Many people have to work more than 8 hours to earn enough money for their family's basic requirements. It causes that many of people be tired and depressed for huge amount of problems they are faced with each day. Due to lack time and financial, people use drugs instead of sporting. It caused many kidney injuries in recent years. I hope an international agreement arises in order to solve this problem.
Submitted by: mahdi (Iran)
07-09-2009 - 08:33:30

6. Good for all

It's a lot of knowledge about painkillers and its adverse effects.
Submitted by: Nadeem (India)
07-09-2009 - 06:58:00

7. Don't take over the recommended dose!

Millions of people take painkiller drugs everyday. However, there are still many people haven't known severe effects of taking over the recommended dose of there drugs even with small amounts. Therefore, this article is really helpful. It provides useful information about the important of taking the right dose. I hope that those who read this article will give back this information to those who don't know about it. Thanks for giving us this helpful information!
Submitted by: Truong Phan (The United States)
07-09-2009 - 05:37:40

8. Pain

I have been on vicodin for almost 4 years, recently my doctor changed it from vicodin hp to narco. I was concerned about all the tylonol. But I feel they shouldnt ban such a good pain killer as vicodin, because if taken right (as such I have been for quite some time) it works rather well. I have had opportunities for stronger like oxycotten ect.. but at the moment feel they are too strong. If the ban vicoden then doctors will have to give pain patient with chronic pain stronger narcotics, as well if they remove the tylonol its higher potential for abuse! I say leave it the way it is, and put stronger warnings on the label to encourage the serious dangers of tylonol overdose. Might as well say we'll ban guns because some people abuse them as well. Come on whats going on in the world. Stupid people that misuse drugs make it hard for us who legitimatly need them and use correctly.
Submitted by: Kenneth Nicklowicz (michigan)
07-09-2009 - 02:53:35

9. the abuse of medications

A lot of people take medicines without medical prescriptions .Not only pain killers , but also other drugs. It is very important to get medicines as doctors prescribe them because there are interactions between ohter medications taken at the same time . Patients should be awared about the risk of taking more of the dose prescribed . It s important the control in the drug stores.
Submitted by: Natalia (Colombia)
07-09-2009 - 02:22:08

10. The dangerous drugs

Here in Brazil is so common the selling of painkillers like Tylenol and other drugs with paracetamol, ibuprofren and acetaminophen. This article is a way to explain the risks higher than benefits of them. So good, particularly to me...
Submitted by: Leandro (Brazil)
07-08-2009 - 15:38:16

11. Limits on widely used pain drug

Before reading this writting I've ever been a very commomly Tylenol user for all kind of pain. If this is harmful for liver, doctors or health organizations should have actions immediately to stop using them widely that no prescription. Thanks a lot VOA Special English for this writting. Thuy Nguyen
Submitted by: Thuy Nguyen (Viet Nam)
07-08-2009 - 15:08:20

12. We should...

We should ask a health professional about drug combinations which could be hazardous. And we should make sure we know what is in the medicines we take and how much of each drug is out of harm's way to take.
Submitted by: Ahmedd Lincoln (The Union of Myanmar)
07-08-2009 - 14:09:54

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