This is the VOA Special English Health Report
People
since ancient times have used aspirin-like medicines to fight pain and reduce
high body temperature.
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| Boxes of aspirin at a drugstore in Chicago |
Modern research
has found other uses for aspirin. The drug acts as a blood thinner. It can help
blood flow past a blockage in an artery. Blockages can cause heart attacks or
strokes. As a result, patients at risk of blockages might be advised by their
doctors to take a low-strength aspirin every day.And
research continues. A new study has shown that aspirin can improve survival in colon
cancer patients.
It
involved about one thousand three hundred patients with colorectal cancer. The
cancer had not spread to other parts of the body yet. The study compared patients
who took three hundred twenty-five milligrams of aspirin at least two times a week
with those who did not use aspirin.
The
study found that the aspirin users had an almost thirty percent lower risk of
dying from their cancer. That was during an average of eleven years after the
cancer was discovered.
Andrew
Chan of Harvard Medical School and Massachusetts General Hospital led the
study. Doctor Chan says the effects appeared especially strong among patients
with tumors expressing an enzyme called COX-2. Two-thirds of colorectal cancers
produce that chemical. Doctor Chan thinks the aspirin works by blocking
it.
The
study appeared last week in the Journal of the American Medical Association. It
was an observational study. In a controlled study, some patients would have
taken aspirin. Others would have received a placebo -- sugar pills -- for
comparison.
Last
year, Doctor Chan reported that a long-term study of almost fifty thousand men
showed that aspirin can help prevent colon cancer. But the effects required at
least six years of regular use. And the greatest risk reductions were in those
who took more than fourteen aspirins per week.
But the
researchers warned that the dangers from such large amounts of aspirin should
be carefully considered.
Aspirin
is a kind of nonsteroidal anti-inflammatory drug, or NSAID. The earlier study
found comparable reductions from the use of other NSAIDs, but not from the use
of acetaminophen.
All of
these drugs have their uses but they also have risks. Aspirin can cause
bleeding in the stomach, the intestines and the brain. People who might want to
consider taking aspirin as a preventative measure should first talk to a
doctor.
And
that's the VOA Special English Health Report, written by Caty Weaver and
available at voaspecialenglish.com. I'm Steve Ember.