In U.S. college basketball action Wednesday, Marque Perry hit a game-winning lay-up with three seconds left in regulation as St. Louis stunned second-ranked Louisville, 59-58.

St. Louis, which entered the game having won only nine of 20 games this season, used a strong defensive effort to end Louisville's 17-game winning streak. Reece Gaines led St. Louis with 28 points.

Anthony Roberson had 15 points and Bonell Colas added 14 as fourth-ranked Florida routed Mississippi, 74-55.

Donatas Zavackas scored 15 points as seventh-ranked Pittsburgh easily got by West Virginia, 82-46.