Iran's supreme leader has dismissed President Bush's charges against Tehran, saying Mr. Bush, like four American presidents before him, will fail in his efforts to uproot Iran's ruling Islamic establishment.

Ayatollah Ali Khamenei told students in Tehran Thursday that Iran's stance has convinced other Islamic countries that it is possible to, in his words, "confront global arrogance and win."

In his State of the Union address Wednesday night, President Bush accused Iran of being the world's primary state sponsor of terror and of pursuing nuclear weapons. He also said the United States stands with the Iranian people as they seek liberty.

Iran's foreign ministry spokesman called the charges "baseless" and said they show Mr. Bush is ignoring what he called Iran's "deep-rooted freedom and democracy."

Some information for this story provided by AP.