Defending champion Maria Sharapova of Russia has reached the third round of the Wimbledon tennis championships, but French Open men's champion Rafael Nadal of Spain is out of the grass-court event.

The second-seeded Sharapova took only 46 minutes to beat 15-year-old Bulgarian Sesil Karatantcheva, 6-0, 6-1. Sharapova next faces Katarina Srebotnik of Slovenia, who ousted South Korea's Yoon Jeong Cho (7-5, 6-4).

In the men's draw, Nadal lost in four sets to unheralded Gilles Muller of Luxembourg (6-4, 4-6, 6-3, 6-4). The fourth-seeded Spaniard was making only his second appearance at the All-England Club.

British Fans had their hearts broken when men's sixth seed Tim Henman lost a five-set match to Russian Dmitry Tursunov (3-6, 6-2, 3-6, 6-3, 8-6). It was the second time in 10 years that the Briton has been eliminated from the second round of the tournament.

Former champion Venus Williams of the United States also advanced with a win over Nicole Pratt of Australia, 7-5, 6-3. Williams next faces Slovakia's Daniela Hantuchova, the 20th seed, who beat Shahar Peer of Israel in three sets (6-2, 2-6, 6-3).

Other winners Thursday included 16th-seeded Nathalie Dechy of France, Cara Black of Zimbabwe, Eleni Daniilidou of Greece and American Jill Craybas.

Some information for this report provided by AP.