A wrist injury has ended the hopes of world ranked number two women's tennis player Kim Clijster to defend her title at the Pacific Life tournament in Indian Wells, California
The Belgian withdrew from the event Saturday suffering from what doctors say is a combination of a bone bruise and tendinitis. Clijsters strained her left wrist during her first round match.
The pullout automatically moved her third round opponent, American Laura Granville, into the fourth round.
Meanwhile, world number one Justin Henin-Hardenne of Belgium advanced to the third round Saturday, easily defeating American Samantha Reeves in straight sets (6-2, 6-2).
In an upset, 14-year-old Bulgarian newcomer Sesil Karatancheva rallied in the third set to dismiss 17th seed Magui Serna of Spain, ranked as 25th in the world.
Other top women's players to advance Saturday were Russian fourth seed Anastasia Myskina, eighth seed Paola Suarez of Argentina, and 16th seed 16-year-old Maria Sharapova of Russia.
In men's second round play, two-time defending champion and eighth seed Lleyton Hewitt of Australia and 2001 champion Andre Agassi of the United States both easily advanced.
Hewitt cruised to a straight sets (6-2, 6-3) victory over Thomas Johansson, and Agassi also took two sets to eliminate his opponent, Spain's David Sanchez (6-2, 6-2).
Unranked Wayne Arthurs of Australia upset sixth seed Rainer Schuettler of Germany (6-1, 7-6). Some information for this report provided by AP and Reuters.