News / Health

Stem Cell Therapy Effective Against HIV Virus in Mice

Stem cells may be thought of as the body's building blocks.  They are master cells which can develop into other types of cells with a specialized function.  Many scientists believe they hold great promise in treating a host of ailments, and there have been good results in some clinical trials. Now, researchers are hoping to start clinical trials in humans using the genetically modified stem cells to fight off the virus which causes AIDS. This, after tests on HIV-infected mice yielded good results.

"The actual stem cells were injected in my arm, said Diana Souza.

Diana Souza says stem cell therapy helped restore full use of her severely fractured arm.

 “It is a miracle. It does work. And I have a good arm to prove it," she said.

Stem cell therapy works by providing new cells to replace the diseased cells and tissues.
At the California Institute of Regenerative Cures, Joseph Anderson is working on stem cell therapy for HIV infection.  So far, he has been working with mice - replacing their immune systems with stem cells engineered with a triple combination of HIV-resistant genes.

"They were able to block HIV infection, maintain a normal immune system in the mice, even though the virus was still there," said Joseph Anderson. "The resistant immune cells were able to maintain a normal immune cell level and maintain a functional immune system.

Anderson says this could provide a possible cure for people who are infected with HIV and have a severely compromised immune system.  He says the genetically-engineered stem cells will help them maintain a normal immune system through genetic resistance just as in the case of the mice.

“If it moves forward in human clinical trials we would be able to maintain a normal human immune system in patients that have HIV infection," he said. "Hopefully they will be able to stop taking antiretroviral drugs that they normally take because the genetically resistant stem cells will be able to fight off the virus in the body of the patients.”

Scientists working on this project say that, ideally, this would be a one-time treatment of stem cells charged with HIV-resistant genes.  They  hope that would generate an entire HIV-resistant immune system - making it possible to take patients off the antiretroviral drugs.

You May Like

Taiwan President Sounds Warning on Future of China Ties

Current Taiwan government has eased once dangerously tough relations with Beijing since 2008, but next year’s presidential election could change that course More

US Presidential Candidates Woo Hispanic Voters

Republican presidential candidate Donald Trump and Democrat Hillary Clinton reached out to Hispanic voters this past week in a bid to boost their voter support More

Video In 'He Named Me Malala,' Guggenheim Finds Normal in Extraordinary

Documentary is a close-up and personal view of young woman who has become of global symbol of courage and inspiration More

Featured Videos

Your JavaScript is turned off or you have an old version of Adobe's Flash Player. Get the latest Flash player.
House Republicans in Chaos as Speaker Favorite Withdrawsi
Jim Malone
October 09, 2015 12:32 AM
The Republican widely expected to become the next speaker of the House of Representatives shocked his colleagues Thursday by announcing he was withdrawing his candidacy. The decision by Majority Leader Kevin McCarthy means the race to succeed retiring Speaker John Boehner is now wide open. VOA National Correspondent Jim Malone reports.

Video House Republicans in Chaos as Speaker Favorite Withdraws

The Republican widely expected to become the next speaker of the House of Representatives shocked his colleagues Thursday by announcing he was withdrawing his candidacy. The decision by Majority Leader Kevin McCarthy means the race to succeed retiring Speaker John Boehner is now wide open. VOA National Correspondent Jim Malone reports.

Video German, US Officials Investigate Volkswagen

German officials have taken steps to restore some of the reputation their car industry has lost after a recent Volkswagen diesel emissions scandal. Authorities have searched Volkswagen headquarters and other locations in an effort to identify the culprits in the creation of software that helps cheat on emission tests. Meanwhile, a group of lawmakers in Washington held a hearing to get to the bottom of the cheating strategy that was first discovered in the United States. Zlatica Hoke reports.

Video Why Are Gun Laws So Hard for Congress to Tackle?

Since taking office, President Barack Obama has spoken out or issued statements about 15 mass shootings. The most recent shooting, in which 10 people were killed at a community college, sparked outrage over the nation's gun laws. But changing those laws isn't as easy as many think. VOA's Carolyn Presutti reports.

Video Hungary Criticized for Handling of Refugees

Amnesty International has accused Hungary of breaking multiple international and European human rights laws in its handling of the refugee crisis. As Henry Ridgwell reports, thousands of migrants and refugees continue to travel through the Balkans to Hungary every day.

Video Iraqi-Kurdish Teachers Vow to Continue Protest

Sixteen people were injured when police used tear gas and rubber bullets to disperse teachers and other public employees who took to the streets in Iraq’s Kurdish north, demanding their salaries from the Kurdish Regional Government (KRG). VOA’s Dilshad Anwar, in Sulaimaniya, caught up with protesting teachers who say they have not been paid for three months. Parke Brewer narrates his report.

Video Syrian Village Community Faces Double Displacement in Lebanon

Driven by war from their village in southwestern Syria, a group of families found shelter in Lebanon, resettling en masse in a half-built university to form one of the biggest settlements of its kind in Lebanon. Three years later, however, they now face being kicked out and dispersed in a country where finding shelter as a refugee can be especially tough. John Owens has more for VOA from the city of Saida, also known as Sidon.

Video Bat Colony: Unusual Tourist Attraction in Texas

The action hero Batman might be everyone’s favorite but real bats hardly get that kind of adoration. Put more than a million of these creatures of the night together and it only evokes images of horror. Sarah Zaman visited the largest urban bat colony in North America to see just how well bat and human get along with each other.

Video Device Shows Promise of Stopping Motion Sickness

It’s a sickening feeling — the dizziness, nausea and vomiting that comes with motion sickness. But a device now being developed could stop motion sickness by suppressing certain signals in the brain. VOA’s Deborah Block reports.

Video Making a Mint

While apples, corn, and cranberries top the list of fall produce in the US, it’s also the time to harvest gum, candy, and toothpaste—or at least the oil that makes them minty fresh. Erika Celeste reports from South Bend, Indiana on the mint harvest.

Video Activists Decry Lagos Slum Demolition

Acting on a court order, authorities in Nigeria demolished a slum last month in the commercial capital, Lagos. But human rights activists say the order was illegal, and the community was razed to make way for a government housing project. Chris Stein has more from Lagos.

Video TPP Agreed, But Faces Stiff Opposition

President Barack Obama promoted the Trans-Pacific Partnership on Tuesday, one day after 12 Pacific Rim nations reached the free trade deal in Atlanta. The controversial pact that would involve about 40 percent of global trade still needs approval by lawmakers in respective countries. Zlatica Hoke reports Obama is facing strong opposition to the deal, including from members of his own party.

Video Ukranian Artist Portrays Putin in an Unusual Way

As Russian President Vladimir Putin was addressing the United Nations in New York last month, he was also being featured in an art exhibition in Washington. It’s not a flattering exhibit. It’s done by a Ukrainian artist in a unique medium. And its creator says it’s not only a work of art - it’s a political statement. VOA’s Tetiana Kharchenko has more.

VOA Blogs