News / Health

Study: Chinese Plant Ingredient Eases Chronic Pain

Corydalis blossoms (Creative Commons-Wikimedia)
Corydalis blossoms (Creative Commons-Wikimedia)
Jessica Berman
Researchers have discovered a natural ingredient in an ancient Chinese plant that relieves chronic pain, including backache.  The compound comes from the roots of the flowering Corydalis herb, which the Chinese have used for centuries to treat pain. 

The Corydalis plant is grown primarily in central eastern China. For thousands of years, people in the Asian country have harvested the plant’s roots or tubers, ground them up and boiled them in vinegar.  The concoction, often processed into a tea, was given to treat pain.  Although it is effective in easing all types of pain, including temporary and inflammatory joint pain, it may have its greatest benefit in treating long-term nagging pain, for which experts say there is no good medicine.
 
A researcher with the University of California Davis, Olivier Civelli, says the active compound in Corydalis identified by researchers is dehydrocorybulbine or DHCB. In animal experiments, DHCB appears to work well in easing low-level chronic pain. The plant is a member of the poppy family.
 
Civelli explains so-called opiod drugs like morphine are often given to treat chronic pain when they should only be prescribed for a short period of time because of their addictive properties. 
 
But DHCB, says Civelli, appears to be both effective and non-addictive in the treatment of persistent pain.
 
“So what we find is our compound does not do that.  It does not lose its effect over time.  Because we have injected to animals for seven days and the analgesic effect [pain relieving] we are seeing stays stable,” says Civelli.
 
Addictive drugs act through a morphine pathway in the brain. But Civelli says it appears DHCB works through another brain transport chemical called a dopamine D2 receptor, which studies suggest plays a role in pain sensation.
 
Civelli and colleagues discovered DHCB as part of the “herbalome” project to identify and catalog the active ingredients in traditional Chinese medicine. 
 
Noting new drug development can cost a $1 billion or more, Civelli says the project seeks to discover cost effective, natural compounds.
 
“Trying to understand ... why [Chinese] people are taking it for 3,000 years or something like that?  And it was efficient.  How many compounds are out there that do something for pain relief? And that is what we are interested in doing now,” says Civelli.
 
Corydalis preparations can be purchased on the Internet but without further testing to make sure they are safe, Civelli does not recommend people take them.
 
An article on discovery of the pain relieving ingredient in the ancient Chinese plant Corydalis is published in the journal Current Biology.

You May Like

Video British Fighters on Frontline of Islamic State Information War

It’s estimated that several hundred British citizens are fighting for Islamic State alongside other foreign jihadists More

Pakistan's Political Turmoil Again Shines Spotlight on Military

Thousands of protesters calling for PM Sharif to step down continue protests in front of parliament, as critics fear political impasse could spur another military coup More

Photogallery Ebola Quarantines Spark Anxiety in Liberian Capital

Food prices rise sharply as residents attempting purchases clash with security forces, leaving one person dead More

Featured Videos

Your JavaScript is turned off or you have an old version of Adobe's Flash Player. Get the latest Flash player.
Native Bees May Help Save Cropsi
X
Deborah Block
August 22, 2014 12:23 AM
U.S. President Barack Obama has called for a federal strategy to promote the health of bees that have been declining. The honeybee has been waning due to parasites, disease and pesticides. Wild bees may be used to take over their role as crop pollinators. Scientists first need to learn a lot more about wild bees, says biologist Sam Droege, who is pioneering the first national inventory on native bees. VOA’s Deborah Block went to his research laboratory in Beltsville, Maryland, to bring you more.
Video

Video Native Bees May Help Save Crops

U.S. President Barack Obama has called for a federal strategy to promote the health of bees that have been declining. The honeybee has been waning due to parasites, disease and pesticides. Wild bees may be used to take over their role as crop pollinators. Scientists first need to learn a lot more about wild bees, says biologist Sam Droege, who is pioneering the first national inventory on native bees. VOA’s Deborah Block went to his research laboratory in Beltsville, Maryland, to bring you more.
Video

Video US Defense Officials Plan for Long-Term Strategy to Contain Islamic State

U.S. defense officials say American air strikes in Iraq have helped deter Islamic State militants for the time being, but that a broad international effort is needed to defeat the extremists permanently. Defense Secretary Chuck Hagel warned Thursday that the group formerly known as the Islamic State in Iraq and the Levant, or ISIL, is better organized, and financially and militarily stronger than any other known terrorist group. Zlatica Hoke has more.
Video

Video Drug-Resistant Malaria Spreads in Southeast Asia

On Thailand’s border with Myanmar, also known as Burma, a malaria research and treatment clinic is stepping up efforts to eliminate a drug-resistant form of the parasite - before it spreads abroad. Steve Sandford reports from Mae Sot, Thailand.
Video

Video Gaza Conflict, Hamas Popularity Challenge Abbas

The Palestinian unity government of Mahmoud Abbas has failed to convince Hamas to agree to Egyptian-negotiated terms with Israel on a Gaza cease-fire. VOA State Department Correspondent Scott Stearns reports on what the Gaza conflict means for President Abbas, with whom U.S. officials have worked for years on a two-state solution to the Israeli-Palestinian conflict.
Video

Video Nigeria's 'Nollywood' Movie Industry Rolls in High Gear

Twenty years after its birth in a video shop in Lagos, Nigeria's "Nollywood" is one of the most prolific film industries on earth. Despite low budgets and whirlwind production schedules, Nigerian films are wildly popular in Africa and industry professionals say they hope, in the future, their films will be as great in quality as they are in quantity. Heather Murdock has more for VOA from Lagos.
Video

Video UN Launches 'Biggest Aid Operation in 30 Years' in Iraq

The United Nations has launched what it describes as one of the biggest aid operations in 30 years in northern Iraq, as hundreds of thousands of refugees flee the extremist Sunni militant group calling itself the Islamic State. As Kurdish and Iraqi forces battle the Sunni insurgents, the fighting has forced more people to flee their homes. Kurdish authorities say the international community must act now to avert a humanitarian catastrophe. Henry Ridgwell reports for VOA from London.
Video

Video Cambodian American Hip Hop Artist Sings of Personal Struggles

A growing underground movement of Cambodian American hip hop artists is rapping about the struggles of living in urban America. Most, if not all of them, are refugees or children of refugees who came to the United States from Cambodia to escape the Khmer Rouge genocide of the 1970s. Through their music, the artists hope to give voice to immigrants who have been struggling quietly for years. Elizabeth Lee reports from Long Beach, California.
Video

Video African Media Tries to Educate Public About Ebola

While the Ebola epidemic continues to claim lives in West Africa, information technology specialists, together with radio and TV reporters, are battling misinformation and prejudice about the disease - using social media to educate the public about the deadly virus. VOA’s George Putic has more.

AppleAndroid