News / Health

Diabetes in Lab Mice Reversed with Natural Compound

The International Diabetes Federation has released data (this week) that indicates the number of people living with diabetes around the world will likely rise from 366 million to 552 million by 2030 if urgent action is not taken. In marking World Diabetes Day this week, the World Health Organization focused attention on India and other developing countries that bear the brunt of the global diabetes epidemic - even as new research offers hope that a cure for the most common form of the disease - Type 2 diabetes - might not be far off.

Many public monuments in New Delhi were illuminated with blue lights on Monday to mark World Diabetes Day. There was good reason for the special notice. India has the world's largest number of diabetics - more than 50 million people and that number is expected to climb to 61 million over the next two decades.

“We want to disseminate the message to the public all over India and also to the world that you (should) beware of diabetes,” said Anup Mishra, chairman of the Fortis Center for Diabetes in India.

The International Diabetes Federation predicts that at least one in 10 people in the world could have diabetes by 2030.  This most common of human disorders is caused mainly by poor diet, excess body weight and physical inactivity.  It not only reduces the quality of life but is also a risk factor for heart disease, stroke and dementia.

A team of researchers in the United States reported recently that it was able to cure Type 2 diabetes in mice. In a study conducted at Washington University School of Medicine in St. Louis,Missouri, the researchers treated mice with a naturally-occurring substance known by its chemical acronym, NMN.

“The bottom line is, NMN has remarkable effects on Type 2 diabetes, at  least in mice,” said Professor Shin-ichiro Imai. He explains the results in mice hold promise because the metabolic processes that NMN influences in mice are likely to be the same in the human body.

“We fed mice a high-fat diet where 40 percent of the calories came from fat - a fatty, nasty diet which the mice liked and eventually they came up (down) with serious Type 2 diabetes. And that’s the model we used to examine the effects of NMN and it works really well.”

The study shows that aging and eating a high-fat diet reduce production of NMN in the body, leading to abnormal metabolic conditions - including diabetes.

The researchers are collaborating with a Japanese company to come up with a grade of the compound that can be used in human trials.

“It will probably take a couple of years, but we are planning to launch a human pilot trial,” said Imai.

The hope is that one day, it will be possible for people to take the compound like a daily vitamin as a way to treat or even prevent Type 2 diabetes.

You May Like

At International AIDS Conference One Goal, Many Paths

The 12,000 delegates attending 20th International AIDS Conference in Melbourne have vastly different visions about how to eradicate disease More

Disasters May Doom Malaysia’s Flag Carrier

Even before loss of two jets loaded with passengers on international flights, company had been operating in red for three years, accumulating deficit of $1.3 billion More

Afghan Presidential Vote Audit Continues Despite Glitches

Process has been marred by walkouts by representatives of two competing candidates, Abdullah Abdullah and Ashraf Ghani More

This forum has been closed.
Comments
     
There are no comments in this forum. Be first and add one

Featured Videos

Your JavaScript is turned off or you have an old version of Adobe's Flash Player. Get the latest Flash player.
Nature of Space Exploration Enters New Agei
X
Elizabeth Lee
July 20, 2014 2:36 AM
Forty-five years ago this month, the first humans walked on the moon. It was during an era of the space race between the United States and the Soviet Union. World politics have changed since then and -- as Elizabeth Lee reports -- so has the nature of space exploration.
Video

Video Nature of Space Exploration Enters New Age

Forty-five years ago this month, the first humans walked on the moon. It was during an era of the space race between the United States and the Soviet Union. World politics have changed since then and -- as Elizabeth Lee reports -- so has the nature of space exploration.
Video

Video Chicago’s Argonne Lab Developing Battery of the Future

In 2012, the U.S. Department of Energy’s Office of Science awarded a $120 million grant to a new technology center focused on battery development - headquartered at Argonne National Laboratory in suburban Chicago, Illinois. As VOA’s Kane Farabaugh reports, there scientists are making the next technological breakthroughs in energy storage.
Video

Video In NW Pakistan, Army Offensive Causes Massive Number of Displaced

Pakistan’s army offensive in North Waziristan has resulted in the large-scale displacement of the local population. VOA's Ayaz Gul reports from northwest Pakistan where authorities say around 80 percent of the estimated 1 million internally displaced persons [IDPs] have settled in Bannu district, while much of the remaining 20 percent are scattered in nearby cities.
Video

Video Kurdish Peshmerga Force Secures Kirkuk, Its Oil

The Kurdistan regional government has sent its Peshmerga troops into the adjacent province of Kirkuk to drive out insurgents, and to secure the area's rich oil fields. By doing this, the regional government has added a fourth province to the three it officially controls. The oil also provides revenue that could make an independent Kurdistan economically strong. VOA’s Jeffrey Young went out with the Peshmerga and filed this report.
Video

Video Malaysia Reeling: Second Air Disaster in Four Months

Malaysia is reeling from the second air disaster in four months involving the country’s flag carrier. Flight 340 vanished in March and despite an extensive search, no debris has been found. And on Thursday, Flight 17, likely hit by a surface-to-air missile, came apart over eastern Ukraine. The two incidents together have left more than 500 people dead. VOA Correspondent Steve Herman reports from Kuala Lumpur.
Video

Video Diplomatic Crisis Grows Over MH17 Plane Crash

The Malaysia Airlines crash in eastern Ukraine is drawing reaction from leaders around the world. With suspicions growing that a surface-to-air missile shot down the aircraft, there are increasing tensions in the international community over who is to blame. Henry Ridgwell reports for VOA from London.
Video

Video Undocumented Immigrants Face Perilous Journey to US, No Guarantees

Every day, hundreds of undocumented immigrants from Central America attempt the arduous journey through Mexico and turn themselves over to U.S. border patrol -- with the hope that they will not be turned away. But the dangers they face along the way are many, and as Ramon Taylor reports from the Rio Grande Valley in Texas, their fate rests on more than just the reception they get at the US border.
Video

Video Scientists Create Blackest Material Ever

Of all the black things in the universe only the infamous "black holes" are so black that not even a tiny amount of light can bounce back. But scientists have managed to create material almost as black, and it has enormous potential use. VOA’s George Putic has more.
Video

Video Fog Collector Transforming Maasai Water Harvesting in Kenya

The Maasai people of Kenya are known for their cattle-herding, nomadic lifestyle. But it's an existence that depends on access to adequate water for their herds and flocks. Lenny Ruvaga reports for VOA, on a "fog collector."

AppleAndroid