News / Health

Exercise Could Stem Alzheimer's Onset

This undated image provided by Merck & Co. shows a cross section of a normal brain (right) and one of a brain damaged by advanced Alzheimer's disease.
This undated image provided by Merck & Co. shows a cross section of a normal brain (right) and one of a brain damaged by advanced Alzheimer's disease.

Related Articles

Head Trauma Linked to Alzheimer’s Disease Plaques

Study indicates history of concussion may increase risk of Alzheimer’s disease by contributing to build-up of Alzheimer’s-associated plaques in brain

Peanut Butter Sniff Test Could Diagnose Alzheimer's

Smell sensitivity can be one of the first things to be affected in cognitive decline

Blood Test Predicts Alzheimer’s Disease

Test could someday help researchers develop drugs for the degenerative brain disorder
Researchers have discovered yet another reason to hit the gym.

A new study of older adults who were at risk of developing Alzheimer’s disease claims that moderate physical activity can prevent shrinkage of the hippocampus, the area of the brain responsible for memory and spatial orientation. It is also the first part of the brain that comes under attack from the devastating disease.

"The good news is that being physically active may offer protection from the neurodegeneration associated with genetic risk for Alzheimer's disease," said Dr. J. Carson Smith, a kinesiology researcher at the University of Maryland School of Public Health who conducted the study in a statement.

"We found that physical activity has the potential to preserve the volume of the hippocampus in those with increased risk for Alzheimer's disease, which means we can possibly delay cognitive decline and the onset of dementia symptoms in these individuals,” he said.

“Physical activity interventions may be especially potent and important for this group," Smith added.

For the study, Smith and his colleagues monitored four groups of “healthy older adults ages 65-89."

The subjects all displayed "normal cognitive abilities over an 18-month period." The volume of their hippocampus also was measured using magnetic resonance imaging (MRI) at the start and finish of the 18 months.

Researchers divided the subjects into four groups, those with high or low Alzheimer’s risk and low or high levels of physical activity. Alzheimer’s risk was determined by the presence of lack of presence of an apolipoprotein called E epsilon 4 allele.

Only the group of high risk and no exercise saw a decrease in hippocampal volume over the 18 months, researchers said. All the other groups maintained hippocampal volume.

"This is the first study to look at how physical activity may impact the loss of hippocampal volume in people at genetic risk for Alzheimer's disease," said Dr. Kirk Erickson, an associate professor of psychology at the University of Pittsburgh in a statement.

"There are no other treatments shown to preserve hippocampal volume in those that may develop Alzheimer's disease,” he added.

“This study has tremendous implications for how we may intervene, prior to the development of any dementia symptoms, in older adults who are at increased genetic risk for Alzheimer's disease," Erickson said.

Smith said the study provides “additional evidence that exercise plays a protective role against cognitive decline.”

The Alzheimer’s Association, which seeks to promote Alzheimer's care, support and research, recommends physical exercise “for maintaining good blood flow to the brain as well as to encourage new brain cells.”

“Growing evidence shows that physical exercise does not have to be strenuous or even require a major time commitment," the association said. "It is most effective when done regularly, and in combination with a brain-healthy diet, mental activity and social interaction.”

Smith said the study suggests the need for more research on how physical activity “may interact with genetics and decrease Alzheimer’s risk.”

Smith had previously shown that walking improved cognitive function in patients already experiencing decline.

He plans to do further research on the effects of exercise intervention on healthy older adults with genetic and other risk factors for developing Alzheimer’s to see how exercise might impact hippocampal volume and subsequent brain function.

According to the Alzheimer’s Foundation of America, more than 5 million Americans suffer from the disease, a number they say will triple by 2050 as the population ages.

The findings are published in the open-access journal Frontiers in Aging Neuroscience.

You May Like

HRW: Egypt's Trial of Morsi ‘Badly Flawed’

Human Rights Watch says former Egypt leader's detention without charge for more than three weeks after his removal from office violated Egyptian law; government rejects criticism More

Photogallery Lancet Report Calls for Major Investment in Surgery

In its report published by The Lancet, panel of experts says people are dying from conditions easily treated in the operating room such as hernia, appendicitis, obstructed labor, and serious fractures More

Music Industry Under Sway of Digital Revolution

Millions of people in every corner of the Earth now can enjoy a vast variety and quantity of music in a way that has never before been possible More

This forum has been closed.
Comments
     
There are no comments in this forum. Be first and add one

Featured Videos

Your JavaScript is turned off or you have an old version of Adobe's Flash Player. Get the latest Flash player.
Study: Insecticide Damaging Wild Bee Populationsi
X
April 24, 2015 10:13 PM
A popular but controversial type of insecticide is damaging important wild bee populations, according to a new study. VOA’s Steve Baragona has more.
Video

Video Study: Insecticide Damaging Wild Bee Populations

A popular but controversial type of insecticide is damaging important wild bee populations, according to a new study. VOA’s Steve Baragona has more.
Video

Video Data Servers Could Heat Private Homes

As every computer owner knows, when their machines run a complex program they get pretty hot. In fact, cooling the processors can be expensive, especially when you're dealing with huge banks of computer servers. But what if that energy could heat private homes? VOA’s George Putic reports that a Dutch energy firm aims to do just that.
Video

Video Cinema That Crosses Borders Showcased at Tribeca Film Festival

Among the nearly 100 feature length films being shown at this year’s Tribeca Film Festival in New York City are more than 20 documentaries and features with international appeal, from a film about a Congolese businessman in China, to documentaries shot in Pakistan and diaspora communities in the U.S., to a poetic look at disaffected South African youth. VOA’s Carolyn Weaver has more.
Video

Video UN Confronts Threat of Young Radicals

The radicalization and recruitment of young people into Islamist extremist groups has become a growing challenge for governments worldwide. On Thursday, the U.N. Security Council heard from experts on the issue, which has become a potent threat to international peace and security. VOA’s Margaret Besheer reports.
Video

Video Growing Numbers of Turks Discover Armenian Ancestry

In a climate of improved tolerance, growing numbers of people in Turkey are discovering their grandmothers were Armenian. Hundreds of thousands of Armenians escaped the mass deportations and slaughter of the early 1900's by forced conversion to Islam. Or, Armenian children were taken in by Turkish families and assimilated. Now their stories are increasingly being heard. Dorian Jones reports from Istanbul that the revelations are viewed as an important step.
Video

Video Migrants Trek Through Western Balkans to Reach EU

Migrants from Africa and other places are finding different routes into the European Union in search of a better life. The Associated Press followed one clandestine group to document their trek through the western Balkans to Hungary. Zlatica Hoke reports that the migrants started using that route about four years ago. Since then, it has become the second-most popular path into Western Europe, after the option of sailing from North Africa to Italy.
Video

Video TIME Magazine Honors Activists, Pioneers Seen as Influential

TIME Magazine has released its list of celebrities, leaders and activists, whom it deems the world’s “most influential” in 2015. VOA's Ramon Taylor reports from New York.
Video

Video US Businesses See Cuba as New Frontier

The Obama administration's opening toward Cuba is giving U.S. companies hope they'll be able to do business in Cuba despite the continuation of the U.S. economic embargo against the communist nation. Some American companies have been able to export some products to Cuba, but the recent lifting of Cuba's terrorism designation could relax other restrictions. As VOA's Daniela Schrier reports, corporate heavy hitters are lining up to head across the Florida Straits - though experts urge caution.
Video

Video Kenya Launches Police Recruitment Drive After Terror Attacks

Kenya launched a major police recruitment drive this week as part of a large-scale effort to boost security following a recent spate of terror attacks. VOA’s Gabe Joselow reports that allegations of corruption in the process are raising old concerns about the integrity of Kenya’s security forces.
Video

Video Japan, China in Race for Asia High-Speed Rail Projects

A lucrative competition is underway in Asia for billions of dollars in high-speed rail projects. Cambodia, India, Indonesia, Malaysia Thailand and Vietnam are among the countries planning to move onto the fast track. They are negotiating with Japan and the upstart Chinese who are locked in a duel to revolutionize transportation across Asia. VOA Correspondent Steve Herman in Bangkok has details.
Video

Video Scientists: Mosquitoes Attracted By Our Genes

Some people always seem to get bitten by mosquitoes more than others. Now, scientists have proved that is really the case - and they say it’s all because of genes. It’s hoped the research might lead to new preventative treatments for diseases like malaria, as Henry Ridgwell reports from London.
Video

Video Bible Museum Coming to Washington DC

Washington is the center of American political power and also home to some of the nation’s most visited museums. A new one that will showcase the Bible has skeptics questioning the motives of its conservative Christian funders. VOA religion correspondent Jerome Socolovsky reports.
Video

Video Armenia and Politics of Word 'Genocide'

A century ago this April, hundreds of thousands of Armenians of the Turkish Ottoman empire were deported and massacred, and their culture erased from their traditional lands. While broadly accepted by the U.N. and at least 20 countries as “genocide”, the United States and Turkey have resisted using that word to describe the atrocities that stretched from 1915 to 1923. But Armenians have never forgotten.
Video

Video Afghan First Lady Pledges No Roll Back on Women's Rights

Afghan First Lady Rula Ghani, named one of Time's 100 Most Influential, says women should take part in talks with Taliban. VOA's Rokhsar Azamee has more from Kabul.
Video

Video New Brain Mapping Techniques Could Ease Chronic Pain

From Boulder, Colorado, Shelley Schlender reports that new methods for mapping pain in the brain are providing validation for chronic pain and might someday guide better treatment.

VOA Blogs