News / Science & Technology

Cockroaches Could Lead to New Antibiotics

The female emerald cockroach wasp leads her prey by the antenna after stinging it to render it docile. The egg she lays on the roach will hatch, burrow inside, and feed on the roach as the wasp larva develops. (Courtesy Gudrun Herzner)
The female emerald cockroach wasp leads her prey by the antenna after stinging it to render it docile. The egg she lays on the roach will hatch, burrow inside, and feed on the roach as the wasp larva develops. (Courtesy Gudrun Herzner)
Most people might see cockroaches as good-for-nothing pests, but this germ-ridden insect could be an indirect source of new antibiotics for humans.

Cockroaches host the larvae of a parasitic type of wasp, which spend their formative days eating the bacteria-laden body of the cockroach from the inside out.

Researchers have discovered the wasp larva secretes chemicals that sanitize the decidedly unsanitary guts of the cockroach.

These germ-killing chemicals could eventually be developed for human uses.

Cockroach cradle

For the developing larvae, “the cockroach is the only food source and the cradle,” says biologist Gudrun Herzner at the University of Regensburg in Germany.

It’s a cradle that needs a good cleaning, because cockroaches spend time in some very unsanitary places, from trash heaps to public toilets, where you’ll find a cornucopia of bacteria, fungi and viruses that can make you, and the emerald wasp larva, sick.

While the young wasp’s hygiene challenges may seem extreme, Herzner says they are basically the same problems we all face. “The larva has to protect, first, its food from degradation by microbes, and then it has to protect itself from foodborne illnesses that these microbes might cause.”

Sanitizer dispenser

As the wasp larva munches its way through the microbe-laden body of the cockroach, it produces generous amounts of a clear liquid.

Herzner and her colleagues found this liquid to contain a blend of antimicrobial substances, according to their study published in the Proceedings of the National Academy of Sciences.

"The larvae seem to disperse this secretion thoroughly inside the cockroach, and in this way sanitize their cockroach hosts,” Herzner says.

One of the chemicals fights the germs that cause tuberculosis; another has a broad range of activity against bacteria, fungi, and viruses such as hepatitis C.

Herzner says it is the first time researchers have found insects using this chemical against microbes.

Insect drugs

But it’s probably not the last insect antimicrobial discovery.

Most antibiotics that doctors use have been discovered among microbes living in the soil, but if researchers turn to the insect world, microbiologist Julian Davies, at the University of British Columbia, says, “You can have a potentially new source of antibiotics. People have been looking at this. Nothing’s come out of it yet, but they’re certainly looking at it.”

Antimicrobials have been discovered everywhere from frog skin to panda blood, but none of them have made it to the medicine cabinet yet.

Davies says it can be hard to isolate useful quantities of the active chemicals in these sources, and they may be difficult chemicals to produce in the lab.

Plus, Davies says, “It’s fine to find an antibiotic, but half of them are toxic.”

Scientists are working to overcome these hurdles.

Bacteria talking?

Davies says these chemicals may be more than just microbe killers. He points to the emerging field of research on microbe-to-microbe chemical communication.

“And you can ask the question, ‘Are they killing each other, or are they talking to each other?’”

But, with antibiotic-resistant infections a growing threat worldwide, killing the microbes is scientists' current priority.

You May Like

South Korea Divided on Response to North’s Cyber Attack

In past five years, officials in Seoul have accused Pyongyang of hacking into banks, government websites, causing chaos and inflicting millions of dollars in damages More

Video Calm Amid Fear in Daily Life in S. Sudan’s Bentiu

Residents have been trying to regain some sense of normalcy, but planning for the future remains uncertain as fear of attacks looms More

2015 Could Be Watershed for Syria Conflict

Republican control of US Senate in January could lead to more aggressive policy against IS militants in Syria - and against regime of Bashar al-Assad More

This forum has been closed.
Comments
     
There are no comments in this forum. Be first and add one

Featured Videos

Your JavaScript is turned off or you have an old version of Adobe's Flash Player. Get the latest Flash player.
Ugandan Doctors Aid Victims of Sudan's Civil Wari
X
Adam Bailes
December 22, 2014 3:45 PM
In Sudan's state of South Kordofan, the number of amputees as result of civil war is in the thousands, but few have access to sufficient medical help. Adam Bailes recently visited the area and says a small team of Ugandan doctors has been providing remote help, producing new prosthetic limbs for those in need.
Video

Video Ugandan Doctors Aid Victims of Sudan's Civil War

In Sudan's state of South Kordofan, the number of amputees as result of civil war is in the thousands, but few have access to sufficient medical help. Adam Bailes recently visited the area and says a small team of Ugandan doctors has been providing remote help, producing new prosthetic limbs for those in need.
Video

Video Jane Monheit Christmas Special

Chanteuse Jane Monheit sings the holiday classic “Have Yourself a Merry Little Christmas,” and explains why it’s her favorite song of the season.
Video

Video Calm Amid Fear in Daily Life in S. Sudan’s Town of Bentiu

Six months ago, Bentiu was a ghost town. The capital of northern Unity State, near South Sudan’s important oil fields, had changed hands several times in fighting between government forces and rebels. Calm returned in November and since then, residents of Bentiu have been trying to regain some sense of normalcy. Bentiu’s market has reopened there are plans to start school again. But fears of new attacks hang heavy, as Benno Muchler reports from Bentiu.
Video

Video US Business Groups Press for Greater Access to Cuba

President Barack Obama's decision to do all he can to ease restrictions on U.S. trade, travel and financial activities with Cuba has drawn criticism from some conservatives and Republicans. People who bring tourists to the island and farmers who want to sell more food to Cuba, however, think they can do a lot more business with Cuba. VOA's Jim Randle reports.
Video

Video Three Cities Bid for Future Obama Presidential Library

President Barack Obama still has two years left in his term in office, but the effort to establish his post-presidential library is already underway. The bid for the Obama Presidential Library is down to four locations in three states -- New York, Hawaii, and Illinois. As VOA’s Kane Farabaugh reports, each of them played an important part in the president’s life before he reached the White House.
Video

Video Fears of More Political Gridlock in 2015

2014 proved to be a difficult year politically for President Barack Obama and a very good year for the U.S. Republican Party. Republican gains in the November midterm elections gave them control of the Senate and House of Representatives for the next two years -- setting the stage for more confrontation and gridlock in the final two years of the Obama presidency. VOA National Correspondent Jim Malone has a preview from Washington.
Video

Video Sudan School Becomes Target of Aerial Attacks

The school dropout rate is at an all-time high in Sudan's South Kordofan state because many schools have been destroyed during the three-year civil war between the government and SPLA-N rebel forces. Adam Bailes visited Sudan's Nuba Mountains' region and reports many children are simply too scared to go to school
Video

Video VOA Reporter Tours Devastated Peshawar School

Islamist militants wearing military uniforms and strapped with explosives attacked a military run school Tuesday in the northwestern Pakistani city of Peshawar. At least 141 people were killed in the horrific attack, most of them young students. VOA reporter Ayaz Gul visited the devastated school and attended the funeral of the principal who courageously tried to save her students from the deadly attack.

All About America

AppleAndroid