News / Health

Researchers: Konzo Impacts Brain Function

A boy sells Cassava leaves at a market in Bunagana, eastern Democratic Republic of Congo, Oct. 19, 2012.
A boy sells Cassava leaves at a market in Bunagana, eastern Democratic Republic of Congo, Oct. 19, 2012.
Art Chimes
Konzo is a crippling disease found mostly in Central and East Africa, and affecting mainly children. Now, an international team of researchers has found that it can affect the brains as well as the bodies of its young victims.
 
Konzo is essentially a result of cyanide poisoning. The cyanide comes from a staple food, a starchy tuber called bitter cassava, when it is not properly prepared. The name konzo comes from the Yaka language and means “tied legs.” And there is no cure.

“It’s irreversible neuromotor damage,” explains Michael J. Boivin, PhD, MPH, of Michigan State University. “It describes some of the abnormalities in walking and movement of the lower limbs, with the toes pointing in, distention of the heels and of the knees that tends to describe the initial onset of the disease.”

Since konzo is a neurological disease, Boivin wanted to see whether it was affecting brain function as well as control of the victim’s lower limbs. So he and his colleagues gave standardized tests to konzo-afflicted children in the Democratic Republic of Congo, as well as to children in the same communities who had no outward signs of the disease.
 
The scientists found that children with konzo scored lower on tests of memory and problem-solving than children without konzo.

“But even the non-konzo children were very at-risk in terms of certain aspects of memory and visual-spatial processing, when compared to children in similar living situations but from non-konzo affected communities,” Boivin said in a telephone interview.

So even children with no physical symptoms had measurable cognitive impairment.

There’s no cure for konzo, so the focus has to be on prevention. Traditional preparation of bitter cassava includes soaking the tuber in water for several days, followed by drying in the sun.  “Those two processing practices," Boivin notes, "will usually break down enough of the cyanide derivatives to make it safe for consumption.”
 
But when communities face drought and other hardships, people take shortcuts with cassava preparation. So Boivin says the way to fight konzo is to stress traditional ways of preparing bitter cassava as well as to promote substituting other foods for at least some of the potentially toxic cassava.

The research by Michael Boivin, principal investigator Desire Tshala-Katumbay, and colleagues is published in the journal Pediatrics.

You May Like

Turkey's Controversial Reform Bill Giving Investors Jitters

Homeland security reform bill will give police new powers in search, seizure, detention and arrests, while restricting the rights of suspects, their attorneys More

Audio Slideshow In Kenyan Prison, Good Grades Are Path to Freedom

Some inmates who get high marks could see their sentences commuted to non-custodial status More

Ali Regained Title in Historic Fight 40 Years Ago

'The Champ' knocked Foreman out to regain crown he had lost 7 years earlier when US government accused him of draft-dodging and boxing officials revoked his license More

This forum has been closed.
Comment Sorting
Comments
     
by: Dr J Howard Bradbury from: Aust Nat University
April 04, 2013 7:54 PM
In collaboration with Drs Banea & Mandombi of PRONANUT & Caritas we have taught village women to use a simple wetting method to remove cyanogens from their cassava flour and have controlled konzo in 4 villages in DRC and 3 more are in progress, Banea et al., Food Chem. Toxicol. 50,(2012), 1517-1523.

Featured Videos

Your JavaScript is turned off or you have an old version of Adobe's Flash Player. Get the latest Flash player.
Victorious Secularists Face Challenge to Form Government in Tunisiai
X
Henry Ridgwell
October 30, 2014 11:39 PM
Official results from Tunisia show the Islamist Ennahda party has failed to win the second free election since the so-called "Arab Spring" uprising in 2011. Ennahda, which handed power to a government of technocrats pending the elections, lost out to the secular party Nidaa Tounes. Henry Ridgwell reports from London that the relatively peaceful poll offers some hope in a volatile region.
Video

Video Victorious Secularists Face Challenge to Form Government in Tunisia

Official results from Tunisia show the Islamist Ennahda party has failed to win the second free election since the so-called "Arab Spring" uprising in 2011. Ennahda, which handed power to a government of technocrats pending the elections, lost out to the secular party Nidaa Tounes. Henry Ridgwell reports from London that the relatively peaceful poll offers some hope in a volatile region.
Video

Video Africa Tells its Story Through Fashion

In Africa, Fashion Week is a riot of colors, shapes, patterns and fabrics - against the backdrop of its ongoing struggle between nature and its fast-growing urban edge. How do these ideas translate into needle and thread? VOA’s Anita Powell visited this year’s Mercedes Benz Fashion Week Africa in Johannesburg to find out.
Video

Video Smugglers Offer Cheap Passage From Turkey to Syria

Smugglers in Turkey offer a relatively cheap passage across the border into Syria. Ankara has stepped up efforts to stem the flow of foreign fighters who want to join Islamic State militants fighting for control of the Syrian border city of Kobani. But porous borders and border guards who can be bribed make illegal border crossings quite easy. Zlatica Hoke has more.
Video

Video China Political Meeting Seeks to Improve Rule of Law

China’s communist leaders will host a top level political meeting this week, called the Fourth Plenum, and for the first time in the party’s history, rule of law will be a key item on the agenda. Analysts and Chinese media reports say the meetings could see the approval of long-awaited measures aimed at giving courts more independence and include steps to enhance an already aggressive and high-reaching anti-corruption drive. VOA’s Bill Ide has more from Beijing.
Video

Video After Decades of Pressure, Luxembourg Drops Bank Secrecy Rules

European Union finance ministers have reached a breakthrough agreement that will make it more difficult for tax cheats to hide their money. The new legislation, which had been blocked for years by countries with a reputation as tax havens, was approved last week after Luxembourg and Austria agreed to lift their vetoes. But as Mil Arcega reports, it doesn’t mean tax cheats have run out of places to keep their money hidden.
Video

Video Kobani Refugees Welcome, Turkey Criticizes, US Airdrop

Residents of Kobani in northern Syria have welcomed the airdrop of weapons, ammunition and medicine to Kurdish militia who are resisting the seizure of their city by Islamic State militants. The Turkish government, however, has criticized the operation. VOA’s Scott Bobb reports from southeastern Turkey, across the border from Kobani.

All About America

AppleAndroid