News / Health

Malaria Vaccine in Clinical Trials in Africa

A young malaria patient in Africa
A young malaria patient in Africa
TEXT SIZE - +
Vidushi Sinha

More than 2 million people die of malaria each year - a child every 45 seconds - with 90 percent of the cases in sub-Saharan Africa. That's why so much importance is placed on developing an effective vaccine.

Organic farmers in Africa complain that insecticides used to control mosquitos that carry the malaria parasitecontaminate their crops and hurt sales.  And this Ugandan nurse says the insecticide of choice is no longer effective.

"It was realized that the mosquito had already developed resistance against the DDT," said Sam Dick Kale.

So in malaria-prone regions, bed nets treated with insecticides, and drug treatment, also are used. That has helped to cut the number of cases nearly in half, but some 800,000 Africans still die from malaria each year, most of them children under five.

Dr. Christian Loucq explains the challenges facing vaccine researchers. He is director of the PATH Malaria Vaccine Initiative that's conducting human trials in sub-Saharan Africa.

“It is difficult to develop a malaria vaccine because we are dealing with a complex organism a parasite which has many, many components and that parasite organism can change, it’s very versatile," said Dr. Loucq. "It’s quite difficult to develop immunity against that parasite.”

Dr. Loucq is hopeful the World Health Organization will approve the new vaccine by 2015.

“It will reduce the number of times a child is going to have malaria, clinical malaria, and it means reducing the number of opportunities for that child to die from malaria," he said.

The Malaria Vaccine Initiative also is trying to develop a second generation vaccine to prevent mosquitos from carrying the malaria parasite.

"Once the mosquito will come to take the blood meal  - the mosquito will take the antibodies that are going to stop the cycle in the mosquito," said Loucq. "Therefore the mosquito will not be in a position to transmit malaria to another child, and that would be a fantastic way to stop the transmission of malaria."

Dr. Loucq says the new vaccine, called RTS,S, will be a major step toward getting rid of malaria. But for that to happen, he says, greater investment in research will be essential.

You May Like

Algerians Vote in Presidential Election

There were few media reports of protests and clashes around the country, but so far no significant violence More

Sharks More Evolved than Previously Thought

The discovery could “profoundly affect our understanding of evolutionary history” More

Pakistan Military Asked to Protect Polio Workers

Request comes as authorities say a Taliban ban on vaccinations in 2012 and deadly attacks on anti-polio teams have prevented thousands of children from getting inoculated More

This forum has been closed.
Comments
     
There are no comments in this forum. Be first and add one

Featured Videos

Your JavaScript is turned off or you have an old version of Adobe's Flash Player. Get the latest Flash player.
Google Buys Drone Companyi
|| 0:00:00
...
 
🔇
X
George Putic
April 15, 2014
In its latest purchase of high-tech companies, Google has acquired a manufacturer of solar-powered drones that can stay in the air almost indefinitely, relaying broadband Internet connection to remote areas. It is seen as yet another step in the U.S. based Web giant’s bid to bring Internet to the whole world. VOA’s George Putic reports.
Video

Video Google Buys Drone Company

In its latest purchase of high-tech companies, Google has acquired a manufacturer of solar-powered drones that can stay in the air almost indefinitely, relaying broadband Internet connection to remote areas. It is seen as yet another step in the U.S. based Web giant’s bid to bring Internet to the whole world. VOA’s George Putic reports.
Video

Video Ray Bonneville Sings the Blues and More on New CD

Singer/songwriter Ray Bonneville has released a new CD called “Easy Gone” with music that reflects his musical and personal journey from French-speaking Canada to his current home in Austin,Texas. The eclectic artist’s fan base extends from Texas to various parts of North America and Europe. VOA’s Greg Flakus reports from Austin.
Video

Video Millions Labor in Pakistan's Informal Economy

The World Bank says that in Pakistan, roughly 70 percent work in the so-called informal sector, a part of the economy that is unregulated and untaxed. VOA's Sharon Behn reports from Islamabad on how the informal sector impact's the Pakistani economy.
Video

Video Passover Celebrates Liberation from Bondage

Jewish people around the world are celebrating Passover, a commemoration of their liberation from slavery in Egypt more than 3,300 years ago. According to scripture, God helped the Jews, led by Moses, escape bondage in Egypt and cross the Red Sea into the desert. Zlatica Hoke reports that the story of the Jewish Exodus resonates with other people trying to escape slave-like conditions.
Video

Video Police Pursue Hate Crime Charges Against Kansas Shooting Suspect

Prosecutors are sifting through the evidence in the wake of Sunday’s shootings in a suburb of Kansas City, Missouri that left three people dead. A suspect in the shootings taken into custody is a white supremacist. As VOA’s Kane Farabaugh reports, he was well-known to law enforcement agencies and human rights groups alike.
Video

Video In Eastern Ukraine, Pro-unity Activists Emerge from Shadows

Amid the pro-Russian uprisings in eastern Ukraine, there is a large body of activists who support Ukrainian unity and reject Russian intervention. Their activities have remained largely underground, but they are preparing to take on their pro-Moscow opponents, as Henry Ridgwell reports from the eastern city of Donetsk.
Video

Video Basket Maker’s Skills Have World Reach

A prestigious craft show in the U.S. capital offers one-of-a-kind creations by more than 120 artists working in a variety of media. As VOA’s Julie Taboh reports from Washington, one artist lucky enough to be selected says sharing her skills with women overseas is just as significant.
Video

Video UN Report Urges Speedier Action to Avoid Climate Disaster

A new United Nations report says the world must switch from fossil fuels to cleaner energy sources to control the effects of climate change. The Intergovernmental Panel on Climate Change released the report (Sunday) following a meeting of scientists and government representatives in Berlin. The comprehensive review follows two recent IPCC reports that detail the certainty of climate change, its impacts and in this most recent report what to do about it. VOA’s Rosanne Skirble has the details.
AppleAndroid