News / Health

Microbicide-Embedded Cervical Ring Could Protect Women From HIV

Scientists have developed a vaginal ring embedded with an antiviral drug that could potentially protect women against the virus that causes AIDS.Scientists have developed a vaginal ring embedded with an antiviral drug that could potentially protect women against the virus that causes AIDS.
x
Scientists have developed a vaginal ring embedded with an antiviral drug that could potentially protect women against the virus that causes AIDS.
Scientists have developed a vaginal ring embedded with an antiviral drug that could potentially protect women against the virus that causes AIDS.
Jessica Berman
Scientists have developed a vaginal ring embedded with an antiviral drug that could potentially protect women against the virus that causes AIDS.

The plastic cervical ring contains MIV-150, a compound developed and being tested by scientists at the non-profit Population Council.

In experiments with macaques, only two of 17 female monkeys fitted ahead of time with the flexible ring became infected after being exposed to SHIV. That virus combines the genetic material of human immunodeficiency virus, or HIV, and a monkey version called SIV. At the same time, 11 of the 16 macaques with vaginal rings that did not contain any active drug became SHIV positive when exposed to the genetically engineered virus.

The results represent an 83 percent protection against the sexually-transmitted infection.

Melissa Robbiani, director of biomedical HIV research at the Population Council, said the microbicide-containing cervical ring would be simple to use and has advantages over short-term protection methods, such as gels or creams that are placed into the vagina or rectum before sexual intercourse.

“It is not dependent upon someone applying it just before intercourse and, on a daily basis, it would be in there hopefully for a month, two months, three months. That’s hopefully going to help the advantage,” said Robbiani.

The ring is similar to a contraceptive ring that’s currently on the market. Once inserted, it is held in place by muscles in the vaginal canal.  The MIV-150 compound, Robbiani believes, acts as a shield in the mucosal tissue at the cellular level, where HIV gains entry into the body.

She said the difference between the drug-infused ring and a topical microbicide may be that the drug delivery device offers continuous protection against the virus with MIV-150, while other microbicides wear off quickly. Testing the monkeys two weeks after exposure to SHIV, researchers found the ring provided significant protection whether it had been inserted two weeks or just 24 hours earlier.

Future experiments will look at how long a ring containing MIV-150 must remain inserted to be fully effective. Researchers also are trying to develop a ring that can be left in place for three months. Robbiani said scientists also are focusing on the drug's formula.

“The next stage would actually be incorporating other antiviral components that would make it even more potent and broader acting. And that would actually be a further strength of this ring,” said Robbiani.

Researchers at the New York-based Population Council describe their work with a vaginal ring to protect against HIV infection in the journal Science Translational Medicine.

You May Like

Lebanese Media Unite to Support Palestinians in Gaza

Joint newscast billed as Arab world’s first unified news bulletin in support of Hamas-controlled Gaza Strip More

Photogallery Australian PM Alleges ‘Coverup’ at MH17 Crash Site

Meanwhile, Russia's ambassador to Malaysia denies plane's black boxes were opened before they were handed over to Malaysian officials More

Despite Advances in AIDS Treatment, Stigma Lingers

Leading immunologist tells VOA that stigma is often what prevents those infected with disease from seeking treatment More

This forum has been closed.
Comment Sorting
Comments
     
by: Yoshi from: Sapporo
September 06, 2012 1:24 AM
Umm, I am afraid some feminists might protest against this procesure.

Featured Videos

Your JavaScript is turned off or you have an old version of Adobe's Flash Player. Get the latest Flash player.
IAEA: Iran Turns its Enriched Uranium Into Less Harmful Formi
X
July 22, 2014 10:26 AM
Iran has converted its stockpiles of enriched uranium into a less dangerous form that is more difficult to use for nuclear weapons, according to the United Nations’ Atomic Energy Agency. The move complies with an interim deal reached with Western powers on Iran's nuclear program last year, in exchange for easing of sanctions. Henry Ridgwell reports for VOA from London.
Video

Video IAEA: Iran Turns its Enriched Uranium Into Less Harmful Form

Iran has converted its stockpiles of enriched uranium into a less dangerous form that is more difficult to use for nuclear weapons, according to the United Nations’ Atomic Energy Agency. The move complies with an interim deal reached with Western powers on Iran's nuclear program last year, in exchange for easing of sanctions. Henry Ridgwell reports for VOA from London.
Video

Video Relic of Saint Draws Catholics Worried About Immigration Issue

A Roman Catholic saint who is a figure of devotion for those crossing the border into the United States is attracting believers concerned about the plight of undocumented immigrants. Mike O'Sullivan reports from Los Angeles, where a relic of Saint Toribio has drawn thousands to local churches.
Video

Video Ukraine Rebels Surrender MH17 Black Boxes

After days of negotiations, a senior separatist leader handed over two black boxes from an airliner downed over eastern Ukraine to Malaysian experts early Tuesday. While on Monday, the U.N. Security Council unanimously demanded that armed groups controlling the crash site allow safe and unrestricted access to the wreckage.
Video

Video In Cambodia, HIV Diagnosis Brings Deadly Shame

Although HIV/AIDS is now a treatable condition, a positive diagnosis is still a life altering experience. In Cambodia, people living with HIV are often disowned by friends, family and the community. This humiliation can be unbearable. We bring you one Cambodian woman’s struggle to overcome a life tragedy and her own HIV positive diagnosis.
Video

Video Nature of Space Exploration Enters New Age

Forty-five years ago this month, the first humans walked on the moon. It was during an era of the space race between the United States and the Soviet Union. World politics have changed since then and -- as Elizabeth Lee reports -- so has the nature of space exploration.
Video

Video Chicago’s Argonne Lab Developing Battery of the Future

In 2012, the U.S. Department of Energy’s Office of Science awarded a $120 million grant to a new technology center focused on battery development - headquartered at Argonne National Laboratory in suburban Chicago, Illinois. As VOA’s Kane Farabaugh reports, there scientists are making the next technological breakthroughs in energy storage.
Video

Video In NW Pakistan, Army Offensive Causes Massive Number of Displaced

Pakistan’s army offensive in North Waziristan has resulted in the large-scale displacement of the local population. VOA's Ayaz Gul reports from northwest Pakistan where authorities say around 80 percent of the estimated 1 million internally displaced persons [IDPs] have settled in Bannu district, while much of the remaining 20 percent are scattered in nearby cities.
Video

Video Kurdish Peshmerga Force Secures Kirkuk, Its Oil

The Kurdistan regional government has sent its Peshmerga troops into the adjacent province of Kirkuk to drive out insurgents, and to secure the area's rich oil fields. By doing this, the regional government has added a fourth province to the three it officially controls. The oil also provides revenue that could make an independent Kurdistan economically strong. VOA’s Jeffrey Young went out with the Peshmerga and filed this report.
Video

Video Malaysia Reeling: Second Air Disaster in Four Months

Malaysia is reeling from the second air disaster in four months involving the country’s flag carrier. Flight 340 vanished in March and despite an extensive search, no debris has been found. And on Thursday, Flight 17, likely hit by a surface-to-air missile, came apart over eastern Ukraine. The two incidents together have left more than 500 people dead. VOA Correspondent Steve Herman reports from Kuala Lumpur.

AppleAndroid