News / Health

New Treatments Emerging for Parkinson's Disease

New Treatments Emerging for Parkinson's Diseasei
X
February 21, 2013 1:08 PM
As people around the world live longer, maladies of old age are becoming more common. And that has doctors searching for ways to treat or prevent diseases like Parkinson's...a degenerative brain condition that usually develops after age 50, and that's known for its disabling physical tremors. As VOA's Carol Pearson reports, medications today can treat the symptoms of Parkinson's, but researchers are hopeful that soon, there will be a way to halt its devastating advance.
Carol Pearson
As people around the world live longer, maladies of old age are becoming more common. And that has doctors searching for ways to treat or prevent diseases like Parkinson's...a degenerative brain condition that usually develops after age 50, and that's known for its disabling physical tremors. Medications today can treat the symptoms of Parkinson's, but researchers are hopeful that soon, there will be a way to halt its devastating advance.

Sarah Taylor knew something was very wrong, but she never dreamed she had Parkinson's disease. "It was a shock. But it was a relief when I found out what was wrong with me, though," she recalled.

Five years ago, when Taylor came to Medstar Washington Hospital Center for treatment, she could hardly move. "When I first came here, it was awful. It was terrible.  I couldn't stand up. I couldn't get up out of the chair.  I was struggling," she stated.

Now she has only mild symptoms. She credits her improvement to following Dr. Mark Lin's advice -- from daily exercise to taking medications on a precise schedule.

Parkinson's disease develops when cells that make dopamine, a brain chemical that controls muscle movement, mysteriously die off. Scientists believe genetics could play a role in a small number of Parkinson's cases. A new U.N. study says man-made chemicals in everyday products are to blame. Other researchers say exposure to toxic chemical pesticides could trigger the disease.

Whatever its cause, the best way to control Parkinson's is to treat it as soon as a diagnosis is made -- usually after the onset of tremors and walking difficulties.  But that can be too late, according to Dr. Hubert Fernandez at the Cleveland Clinic.

"By this time, though, a considerable amount of degeneration has already occurred in the brain," Fernandez explained. "Ideally, we would like to have a test that is specific for Parkinson's disease.  And, ideally, we would like to have that test become positive even before we see the shaking."

There's currently no such test for Parkinson's, but at Northwestern University, researchers think they might have found a way to slow its progression.

"We looked at the cells in the brain that were most vulnerable to the disease. What we saw was they allowed lots and lots of calcium into their cell bodies," said Jim Surmeier, Physiologist who spoke to VOA by Skype.

The calcium eventually killed dopamine-producing cells and triggered Parkinson's symptoms. But the Northwestern University scientists found a drug that limits the brain cells' uptake of calcium, without harmful side effects. In a Skype interview, co-researcher Tanya Simuni told VOA another clinical trial is being planned. "The primary question to be answered in this study is whether the drug is effective in slowing the progression of Parkinson's disease disability," she said. 

Current drugs used to control the tremors and walking difficulties work well for about five to ten years. If scientists could develop a new therapy that could double or triple that time, it would enable Sarah Taylor and the ten million other people living with Parkinson's disease around the world to lead much more normal lives.

You May Like

Egypt's Suez Canal Dreams Tempered by Continued Unrest

Seen as a potential driver of recovery, Cairo’s plan to expand waterway had been raising hopes to give country much needed economic boost More

Ebola Maternity Ward in Sierra Leone First of its Kind

Country already had one of world's highest maternal mortality rates before Ebola arrived, virus has added even more complications to health care More

Malaysia Flight 370 Disappearance Ruled Accident

Aircraft disappeared on March 8, 2014; with ruling, families of 239 passengers and crew can now seek compensation from airline More

This forum has been closed.
Comment Sorting
Comments
     
by: Peter Denos from: Norwalk, Ohio
February 25, 2013 8:16 AM
I'm wondering what the new drug is and if it is available at the Cleveland Clinic? I'm wondering if it will help someone with advanced parkinsons like my brother?

Featured Videos

Your JavaScript is turned off or you have an old version of Adobe's Flash Player. Get the latest Flash player.
Groundbreaking Hand-Painted Documentary About Van Gogh in Productioni
X
George Putic
January 29, 2015 9:43 PM
The troubled life of the famous 19th century Dutch painter Vincent van Gogh has been told through many books and films, but never in the way a group of filmmakers now intends to do. "Loving Vincent " will be the first ever feature-length film made of animated hand-painted images, done in the style of the late artist. VOA’s George Putic reports.
Video

Video Groundbreaking Hand-Painted Documentary About Van Gogh in Production

The troubled life of the famous 19th century Dutch painter Vincent van Gogh has been told through many books and films, but never in the way a group of filmmakers now intends to do. "Loving Vincent " will be the first ever feature-length film made of animated hand-painted images, done in the style of the late artist. VOA’s George Putic reports.
Video

Video Rock-Consuming Organisms Alter Views of Life Processes

Scientists thought they knew much about how life works, until a discovery more than two decades ago challenged conventional beliefs. Scientists found that there are organisms that breathe rocks. And it is only recently that the scientific community is accepting that there are organisms that could get energy out of rocks. Correspondent Elizabeth Lee reports.
Video

Video Paris Attacks Highlight Global Weapons Black Market

As law enforcement officials piece together how the Paris and Belgian terror cells carried out their recent attacks, questions are being asked about how they obtained military grade assault weapons - which are illegal in the European Union. As VOA's Jeff Swicord reports, experts say there is a very active worldwide black market for these weapons, and criminals and terrorists are buying.
Video

Video Activists Accuse China of Targeting Religious Freedom

The U.S.-based Chinese religious rights group ChinaAid says 2014 was the worst year for religious freedom in China since the end of the Cultural Revolution. As Ye Fan reports, activists say Beijing has been tightening religious controls ever since Chinese leader Xi Jinping came to office. Hu Wei narrates.
Video

Video Super Bowl Ads Compete for Eyes on TV, Web

Super Bowl Sunday (Feb. 1) is about more than just the NFL's American football championship and big parties to watch the game. Viewers also tune in for the world famous commercials that send Facebook and Twitter abuzz. Daniela Schrier reports on the social media rewards for America’s priciest advertising.
Video

Video Theologians Cast Doubt on Morality of Drone Strikes

In 2006, stirred by photos of U.S. soldiers mistreating Iraqi prisoners, a group of American faith leaders and academics launched the National Religious Campaign Against Torture. It played an important role in getting Congress to investigate, and the president to ban, torture. VOA's Jerome Socolovsky reports.
Video

Video Freedom on Decline Worldwide, Report Says

The state of global freedom declined for the ninth consecutive year in 2014, according to global watchdog Freedom House's annual report released Wednesday. VOA's William Gallo has more.
Video

Video MRI Seems to Help Diagnose Prostate Cancer, Preliminary Study Shows

Just as with mammography used to detect breast cancer, there's a lot of controversy about tests used to diagnose prostate cancer. Fortunately, a new study shows doctors may now have a more reliable way to diagnose prostate cancer for high risk patients. More from VOA's Carol Pearson.
Video

Video Smartphones About to Make Leap, Carry Basic Senses

Long-distance communication contains mostly sounds and pictures - for now. But scientists in Britain say they are close to creating additions for our smartphones that will make it possible to send taste, smell and even a basic touch. VOA’s George Putic reports.
Video

Video Former Sudan 'Lost Boy' Becomes Chess Master in NYC

In the mid-1980’s, thousands of Sudanese boys escaped the country's civil war by walking for weeks, then months and finally for more than a year, up to 1,500 kilometers across three countries. The so-called Lost Boys of the Sudan had little time for games. But one of them later mastered the game of chess, and now teaches it to children in the New York area. VOA’s Bernard Shusman in New York has his story.
Video

Video NASA Monitors Earth’s Vital Signs From Space

The U.S. space agency, NASA, is wrapping up its busiest 12-month period in more than a decade, with three missions launched in 2014 and two this month, one in early January and the fifth scheduled for January 29. As VOA’s Rosanne Skirble reports, the instruments being lifted into orbit are focused on Earth’s vital life support systems and how they are responding to a warmer planet.
Video

Video Crowded Republican Presidential Field Off to Early Start for 2016

It seems early, but the 2016 U.S. presidential election campaign is already heating up. Though no one has officially announced a candidacy, several potential Republican contenders have been busy speaking to conservative groups about making a White House run next year. Many of the possible contenders are critical of the Obama administration’s foreign policy record. VOA national correspondent Jim Malone reports.

Circumventing Censorship

An Internet Primer for Healthy Web Habits

As surveillance and censoring technologies advance, so, too, do new tools for your computer or mobile device that help protect your privacy and break through Internet censorship.
More

All About America

AppleAndroid