News / Health

    New Treatments Emerging for Parkinson's Disease

    New Treatments Emerging for Parkinson's Diseasei
    X
    February 21, 2013 1:08 PM
    As people around the world live longer, maladies of old age are becoming more common. And that has doctors searching for ways to treat or prevent diseases like Parkinson's...a degenerative brain condition that usually develops after age 50, and that's known for its disabling physical tremors. As VOA's Carol Pearson reports, medications today can treat the symptoms of Parkinson's, but researchers are hopeful that soon, there will be a way to halt its devastating advance.
    Carol Pearson
    As people around the world live longer, maladies of old age are becoming more common. And that has doctors searching for ways to treat or prevent diseases like Parkinson's...a degenerative brain condition that usually develops after age 50, and that's known for its disabling physical tremors. Medications today can treat the symptoms of Parkinson's, but researchers are hopeful that soon, there will be a way to halt its devastating advance.

    Sarah Taylor knew something was very wrong, but she never dreamed she had Parkinson's disease. "It was a shock. But it was a relief when I found out what was wrong with me, though," she recalled.

    Five years ago, when Taylor came to Medstar Washington Hospital Center for treatment, she could hardly move. "When I first came here, it was awful. It was terrible.  I couldn't stand up. I couldn't get up out of the chair.  I was struggling," she stated.

    Now she has only mild symptoms. She credits her improvement to following Dr. Mark Lin's advice -- from daily exercise to taking medications on a precise schedule.

    Parkinson's disease develops when cells that make dopamine, a brain chemical that controls muscle movement, mysteriously die off. Scientists believe genetics could play a role in a small number of Parkinson's cases. A new U.N. study says man-made chemicals in everyday products are to blame. Other researchers say exposure to toxic chemical pesticides could trigger the disease.

    Whatever its cause, the best way to control Parkinson's is to treat it as soon as a diagnosis is made -- usually after the onset of tremors and walking difficulties.  But that can be too late, according to Dr. Hubert Fernandez at the Cleveland Clinic.

    "By this time, though, a considerable amount of degeneration has already occurred in the brain," Fernandez explained. "Ideally, we would like to have a test that is specific for Parkinson's disease.  And, ideally, we would like to have that test become positive even before we see the shaking."

    There's currently no such test for Parkinson's, but at Northwestern University, researchers think they might have found a way to slow its progression.

    "We looked at the cells in the brain that were most vulnerable to the disease. What we saw was they allowed lots and lots of calcium into their cell bodies," said Jim Surmeier, Physiologist who spoke to VOA by Skype.

    The calcium eventually killed dopamine-producing cells and triggered Parkinson's symptoms. But the Northwestern University scientists found a drug that limits the brain cells' uptake of calcium, without harmful side effects. In a Skype interview, co-researcher Tanya Simuni told VOA another clinical trial is being planned. "The primary question to be answered in this study is whether the drug is effective in slowing the progression of Parkinson's disease disability," she said. 

    Current drugs used to control the tremors and walking difficulties work well for about five to ten years. If scientists could develop a new therapy that could double or triple that time, it would enable Sarah Taylor and the ten million other people living with Parkinson's disease around the world to lead much more normal lives.

    You May Like

    How Aleppo Rebels Plan to Withstand Assad's Siege

    Rebels in Aleppo are laying plans to withstand a siege by Syrian President Bashar al-Assad’s forces in likelihood the regime cuts a final main supply line running west of city

    Probe Targeting China's Statistic Head Sparks Concern

    Economists now asking what prompted government to launch an investigation only months after Wang Baoan had been vetted for crucial job

    HRW: Both Sides in Ukraine Conflict Targeted, Used Schools

    Rights group documents how both sides in Ukraine conflict carried out attacks on schools and used them for military purposes

    This forum has been closed.
    Comment Sorting
    Comments
         
    by: Peter Denos from: Norwalk, Ohio
    February 25, 2013 8:16 AM
    I'm wondering what the new drug is and if it is available at the Cleveland Clinic? I'm wondering if it will help someone with advanced parkinsons like my brother?

    Featured Videos

    Your JavaScript is turned off or you have an old version of Adobe's Flash Player. Get the latest Flash player.
    Russia's Car Sales Shrink Overall, But Luxury and Economy Models See Growthi
    X
    February 10, 2016 5:54 AM
    Car sales in Russia dropped by more than a third in 2015 because of the country's economic woes. But, at the extreme ends of the car market, luxury vehicles and some economy brands are actually experiencing growth. VOA's Daniel Schearf reports from Moscow.
    Video

    Video Russia's Car Sales Shrink Overall, But Luxury and Economy Models See Growth

    Car sales in Russia dropped by more than a third in 2015 because of the country's economic woes. But, at the extreme ends of the car market, luxury vehicles and some economy brands are actually experiencing growth. VOA's Daniel Schearf reports from Moscow.
    Video

    Video Civil Rights Pioneer Remembers Struggle for Voting Rights

    February is Black History Month in the United States. The annual, month-long national observance pays tribute to important people and events that shaped the history of African Americans. VOA's Chris Simkins reports how one man fought against discrimination to help millions of blacks obtain the right to vote
    Video

    Video Jordanian Theater Group Stages Anti-Terrorism Message

    The lure of the self-styled “Islamic State” has many parents worried about their children who may be susceptible to the organization’s online propaganda. Dozens of Muslim communities in the Middle East are fighting back -- giving young adults alternatives to violence. One group in Jordan is using dramatic expression a send a family message. Mideast Broadcasting Network correspondent Haider Al Abdali shared this report with VOA. It’s narrated by Bronwyn Benito
    Video

    Video Migrant Crisis Fuels Debate Over Britain’s Future in EU

    The migrant crisis in Europe is fueling the debate in Britain ahead of a referendum on staying in the European Union that may be held this year. Prime Minister David Cameron warns that leaving the EU could lead to thousands more migrants arriving in the country. Meanwhile, tension is rising in Calais, France, where thousands of migrants are living in squalid camps. VOA's Henry Ridgwell reports.
    Video

    Video Valentine's Day Stinks for Lebanese Clowns

    This weekend, on Valentine's Day in Lebanon, love is not the only thing in the air. More than half a year after the country's trash crisis began, the stink of uncollected garbage remains on the streets. Step forward "Clown Me In," a group of clowns who use their skills for activism. Before the most romantic day of the year the clowns have released their unusual take on love in Lebanon -- in a bid to keep the pressure up and get the trash off the streets. John Owens reports from Beirut.
    Video

    Video Families Flee Aleppo for Kurdish Regions in Syria

    Not all who flee the fighting in Aleppo are trying to cross the border into Turkey. A VOA reporter caught up with several families heading for Kurdish-held areas of northern Syria.
    Video

    Video Rocky Year Ahead for Nigeria Amid Oil Price Crash

    The global fall in the price of oil has rattled the economies of many petroleum exporters, and Africa’s oil king Nigeria is no exception. As Chris Stein reports from Lagos, analysts are predicting a rough year ahead for the continent’s top producer of crude.
    Video

    Video 'No Means No' Program Targets Sexual Violence in Kenya

    The organizers of an initiative to reduce and stop rape in the informal settlements around Kenya's capital say their program is having marked success. Girls are taking self-defense classes while the boys are learning how to protect the girls and respect them. Lenny Ruvaga reports from Nairobi.
    Video

    Video Chocolate Lovers Get a Sweet History Lesson

    Observed in many countries around the world, Valentine’s Day is sometimes celebrated with chocolate festivals. But at a festival near Washington, the visitors experience a bit more than a sugar rush. They go on a sweet journey through history. VOA’s June Soh takes us to the festival.
    Video

    Video 'Smart' Bandages Could Heal Wounds More Quickly

    Simple bandages are usually seen as the first line of attack in healing small to moderate wounds and burns. But scientists say new synthetic materials with embedded microsensors could turn bandages into a much more valuable tool for emergency physicians. VOA’s George Putic reports.
    Video

    Video Researchers Use 3-D Printer to Produce Transplantable Body Parts

    Human organ transplants have become fairly common around the world in the past few decades. Researchers at various universities are coordinating their efforts to find solutions -- including teams at the University of Pennsylvania and Rice University in Houston that are experimenting with a 3-D printer -- to make blood vessels and other structures for implant. As VOA’s Greg Flakus reports from Houston, they are also using these artificial body parts to seek ways of defeating cancerous tumors.
    Video

    Video Helping the Blind 'See' Great Art

    There are 285 million blind and visually impaired people in the world who are unable to enjoy visual art at a museum. One New York photographer is trying to fix this situation by making tangible copies of the world’s masterpieces. VOA correspondent Victoria Kupchinetsky was there as visually impaired people got a feel for great art. Joy Wagner narrates her report.
    Video

    Video German Artists to Memorialize Refugees With Life Jacket Exhibit

    Sold in every kind of shop in some Turkish port towns, life jackets have become a symbol of the refugee crisis that brought a million people to Europe in 2015.  On the shores of Lesbos, Greece, German artists collect discarded life jackets as they prepare an art installation they plan to display in Germany.  For VOA, Hamada Elrasam has this report from Lesbos, Greece.
    Video

    Video E-readers Help Ease Africa's Book Shortage

    Millions of people in Africa can't read, and there's a chronic shortage of books. A non-profit organization called Worldreader is trying to help change all that one e-reader at a time. VOA’s Deborah Block tells us about a girls' school in Nairobi, Kenya where Worldreader is making a difference.