News / Health

New Treatments Emerging for Parkinson's Disease

New Treatments Emerging for Parkinson's Diseasei
X
February 21, 2013 1:08 PM
As people around the world live longer, maladies of old age are becoming more common. And that has doctors searching for ways to treat or prevent diseases like Parkinson's...a degenerative brain condition that usually develops after age 50, and that's known for its disabling physical tremors. As VOA's Carol Pearson reports, medications today can treat the symptoms of Parkinson's, but researchers are hopeful that soon, there will be a way to halt its devastating advance.
Carol Pearson
As people around the world live longer, maladies of old age are becoming more common. And that has doctors searching for ways to treat or prevent diseases like Parkinson's...a degenerative brain condition that usually develops after age 50, and that's known for its disabling physical tremors. Medications today can treat the symptoms of Parkinson's, but researchers are hopeful that soon, there will be a way to halt its devastating advance.

Sarah Taylor knew something was very wrong, but she never dreamed she had Parkinson's disease. "It was a shock. But it was a relief when I found out what was wrong with me, though," she recalled.

Five years ago, when Taylor came to Medstar Washington Hospital Center for treatment, she could hardly move. "When I first came here, it was awful. It was terrible.  I couldn't stand up. I couldn't get up out of the chair.  I was struggling," she stated.

Now she has only mild symptoms. She credits her improvement to following Dr. Mark Lin's advice -- from daily exercise to taking medications on a precise schedule.

Parkinson's disease develops when cells that make dopamine, a brain chemical that controls muscle movement, mysteriously die off. Scientists believe genetics could play a role in a small number of Parkinson's cases. A new U.N. study says man-made chemicals in everyday products are to blame. Other researchers say exposure to toxic chemical pesticides could trigger the disease.

Whatever its cause, the best way to control Parkinson's is to treat it as soon as a diagnosis is made -- usually after the onset of tremors and walking difficulties.  But that can be too late, according to Dr. Hubert Fernandez at the Cleveland Clinic.

"By this time, though, a considerable amount of degeneration has already occurred in the brain," Fernandez explained. "Ideally, we would like to have a test that is specific for Parkinson's disease.  And, ideally, we would like to have that test become positive even before we see the shaking."

There's currently no such test for Parkinson's, but at Northwestern University, researchers think they might have found a way to slow its progression.

"We looked at the cells in the brain that were most vulnerable to the disease. What we saw was they allowed lots and lots of calcium into their cell bodies," said Jim Surmeier, Physiologist who spoke to VOA by Skype.

The calcium eventually killed dopamine-producing cells and triggered Parkinson's symptoms. But the Northwestern University scientists found a drug that limits the brain cells' uptake of calcium, without harmful side effects. In a Skype interview, co-researcher Tanya Simuni told VOA another clinical trial is being planned. "The primary question to be answered in this study is whether the drug is effective in slowing the progression of Parkinson's disease disability," she said. 

Current drugs used to control the tremors and walking difficulties work well for about five to ten years. If scientists could develop a new therapy that could double or triple that time, it would enable Sarah Taylor and the ten million other people living with Parkinson's disease around the world to lead much more normal lives.

You May Like

For Lebanon-based Refugees, Desperation Fuels Perilous Passage

In a war that has caused an estimated three million people to flee Syria, efforts to make perilous sea journey in search of asylum expected to increase More

South African Brewer Tackles Climate Change

Mega-brewer SAB Miller sent delegates to climate summit in Peru, says it is one of many private companies taking their own steps to fight climate change More

Indonesia Reports Increase in Citizens Joining Islamic State

Officials say more than 350 of its citizens are now in Syria or Iraq to fight with Islamic State - 50 more than last month More

This forum has been closed.
Comment Sorting
Comments
     
by: Peter Denos from: Norwalk, Ohio
February 25, 2013 8:16 AM
I'm wondering what the new drug is and if it is available at the Cleveland Clinic? I'm wondering if it will help someone with advanced parkinsons like my brother?

Featured Videos

Your JavaScript is turned off or you have an old version of Adobe's Flash Player. Get the latest Flash player.
Will Pakistan School Shooting Galvanize Pakistan Against Extremism?i
X
Ayesha Tanzeem
December 17, 2014 11:54 AM
The attack on a military school in Pakistan’s northwest city of Peshawar left 141 dead, including 132 children. Strong statements of condemnation poured in from across the world. The country announced three days of mourning, and the leadership, both political and military, promised retribution. VOA's Ayesha Tanzeem looks at how likely the Pakistani government is to clamp down on all extremist groups.
Video

Video Will Pakistan School Shooting Galvanize Pakistan Against Extremism?

The attack on a military school in Pakistan’s northwest city of Peshawar left 141 dead, including 132 children. Strong statements of condemnation poured in from across the world. The country announced three days of mourning, and the leadership, both political and military, promised retribution. VOA's Ayesha Tanzeem looks at how likely the Pakistani government is to clamp down on all extremist groups.
Video

Video ‘Anti-Islamization’ Marches Increase Tensions In Germany

Anti-immigrant rallies in Germany have been building in recent weeks, peaking Monday night in the city of Dresden where tens of thousands of people turned out to demonstrate against what they call the ‘Islamization’ of the West. Germany has offered asylum to more Syrian refugees than any other country, and this appears to have set off the protests. Henry Ridgwell reports from London.
Video

Video Aceh Rebuilt Decade After Tsunami, But Scars Remain

On December 26, 2004 there was an earthquake in the Indian Ocean so powerful it caused the Earth’s axis to wobble a few centimeters. Onshore on the island of Sumatra, the resulting tsunami was devastating. A decade later, VOA Correspondent Steve Herman reports from Banda Aceh, Indonesia, where although there is little remaining evidence of the physical devastation, the psychological scars among survivors remain.
Video

Video Refugees Living in Kenya Long for Peace in the Home Countries

Kenya is host to numerous refugees seeking safe haven from conflict. Immigrants from Somalia face challenges in their new lives in Kenya. Ahead of International Migrants Day (December 18) Lenny Ruvaga has more for VOA News from the Kenyan capital.
Video

Video Turkey's Authoritarianism Dismays Western Allies

The Turkish government has been defiant in the face of criticism at home and abroad for its raids targeting opposition media. The European Union on Monday expressed dismay after President Recep Tayyip Erdogan lashed out at Brussels for criticizing his government's action. Turkey's bid to be considered for EU membership has been on hold while critics accuse the NATO ally of increasingly authoritarian rule. Zlatica Hoke reports.
Video

Video US-China Year in Review: Hong Kong to Climate Change

The United States is pushing for a code of conduct to resolve territorial disputes in the South China Sea as it works to improve commercial ties with Beijing. VOA State Department correspondent Scott Stearns reports on a year of U.S. policy toward China from Hong Kong to climate change.
Video

Video Japanese Leader’s Election Win Raises Potential for Conflict with Neighbors

Japan’s Prime Minister Shinzo Abe and his allies easily won a two-thirds majority in parliament Sunday, even though the country has slipped into recession under his conservative policies. VOA’s Brian Padden reports from Seoul, that the prime minister’s victory will empower him to continue economic reforms but also pursue a nationalist agenda that will likely increase tensions with Japan’s neighbors.
Video

Video Nuba Mountain Families Hide in Caves to Escape Aerial Bombings

Despite ongoing peace talks between Sudan's government and the rebel Sudan People’s Liberation Movement-North, or SPLM-N, daily aerial attacks continue in South Kordofan province’s Nuba Mountains. Adam Bailes was there and reports for VOA that government forces are targeting civilian areas, rather than military positions, with their daily bombardments.

All About America

AppleAndroid