News / Health

Nicotine May Increase Risk of Alzheimer’s Disease

FILE - A woman smokes a cigarette in a parking lot in Bangkok, Thailand, May 27, 2010.FILE - A woman smokes a cigarette in a parking lot in Bangkok, Thailand, May 27, 2010.
x
FILE - A woman smokes a cigarette in a parking lot in Bangkok, Thailand, May 27, 2010.
FILE - A woman smokes a cigarette in a parking lot in Bangkok, Thailand, May 27, 2010.
Jessica Berman
The first scientific study to look at the role of cigarette smoke in the development of Alzheimer’s disease finds it may trigger or worsen the condition in older people who are at risk for this most common form of senile dementia.  

Alzheimer’s disease is usually a condition of old age.  Experts say people who live long enough - generally into their 70s, 80s and 90s -- are at significantly increased risk of developing the neurodegenerative disease, which not only robs people of their memories but also of their mobility. Alzheimer's is incurable and leads eventually to death.

Now, a new study suggests cigarette smoking may trigger or hasten the development of dementia.  The research only involved mice, but the findings offer human tobacco smokers another compelling reason to kick the habit.

Claudio Soto is a professor of neurology at the University of Texas Health Science Center at Houston Medical School. Working with transgenic mice bred to develop a human version of Alzheimer’s, he and his colleagues exposed one group to second-hand smoke, as if they were non-smokers inhaling the smoke of others.  Another group of rodents was exposed to a cloud of smoke inhaled by light smokers, an amount equivalent to one or two cigarettes per day.

The results, says Soto, were compared to transgenic mice that were not exposed to any cigarette smoke.

“We found that animals that were exposed to cigarette smoke have much more severe and early manifestations of Alzheimer’s disease damage in the brain,” he said.

In a future experiment, Soto plans to study the effects of greater amounts of smoke on rodents' brains.  

This undated image provided by Merck & Co., shows a cross section of a normal brain (right) and one of a brain damaged by advanced Alzheimer's disease, December 3, 2012This undated image provided by Merck & Co., shows a cross section of a normal brain (right) and one of a brain damaged by advanced Alzheimer's disease, December 3, 2012
x
This undated image provided by Merck & Co., shows a cross section of a normal brain (right) and one of a brain damaged by advanced Alzheimer's disease, December 3, 2012
This undated image provided by Merck & Co., shows a cross section of a normal brain (right) and one of a brain damaged by advanced Alzheimer's disease, December 3, 2012
Researchers say the plaques and tangles found in the mice are similar to those telltale signs found when the brains of human Alzheimer’s patients are autopsied.  

Soto says most cases of Alzheimer’s in humans are sporadic, meaning there is no genetic defect that causes the disease.  But aging increases risk, he says, especially if people are exposed to environmental risk factors such as cigarette smoke.

For that reason, Soto says it's possible that smokers who kick the habit have a good chance of preventing the neurodegenerative disorder.

“Based on our observations and the epidemiological studies, I would think quitting smoking would reduce the risk of Alzheimer’s disease,” he said.

Soto and colleagues describe the link between cigarette smoke and Alzheimer’s disease in the journal Nature Communications.

You May Like

WHO: Anti-Ebola Efforts Should Focus on West Africa

Official says WHO is 'reasonably confident' countries bordering those hardest hit by the Ebola outbreak are not seeing the virus crossing their borders More

South Sudan Crisis Threatens Development

Economic costs and lost development opportunities in South Sudan have erased what little progress the country has made since independence in 2011 More

Ukrainian PM Warns: Russia May Try to Disrupt Sunday Poll

Arseniy Yatsenyuk orders full security mobilization for parliamentary election to prevent ‘terrorist acts’ from being carried out More

Featured Videos

Your JavaScript is turned off or you have an old version of Adobe's Flash Player. Get the latest Flash player.
After Decades of Pressure, Luxembourg Drops Bank Secrecy Rulesi
X
October 21, 2014 12:20 AM
European Union finance ministers have reached a breakthrough agreement that will make it more difficult for tax cheats to hide their money. The new legislation, which had been blocked for years by countries with a reputation as tax havens, was approved last week after Luxembourg and Austria agreed to lift their vetoes. But as Mil Arcega reports, it doesn’t mean tax cheats have run out of places to keep their money hidden.
Video

Video After Decades of Pressure, Luxembourg Drops Bank Secrecy Rules

European Union finance ministers have reached a breakthrough agreement that will make it more difficult for tax cheats to hide their money. The new legislation, which had been blocked for years by countries with a reputation as tax havens, was approved last week after Luxembourg and Austria agreed to lift their vetoes. But as Mil Arcega reports, it doesn’t mean tax cheats have run out of places to keep their money hidden.
Video

Video Kobani Refugees Welcome, Turkey Criticizes, US Airdrop

Residents of Kobani in northern Syria have welcomed the airdrop of weapons, ammunition and medicine to Kurdish militia who are resisting the seizure of their city by Islamic State militants. The Turkish government, however, has criticized the operation. VOA’s Scott Bobb reports from southeastern Turkey, across the border from Kobani.
Video

Video China Political Meeting Seeks to Improve Rule of Law

China’s communist leaders will host a top level political meeting this week, called the Fourth Plenum, and for the first time in the party’s history, rule of law will be a key item on the agenda. Analysts and Chinese media reports say the meetings could see the approval of long-awaited measures aimed at giving courts more independence and include steps to enhance an already aggressive and high-reaching anti-corruption drive. VOA’s Bill Ide has more from Beijing.
Video

Video US ‘Death Cafes’ Put Focus on the Finale

In contemporary America, death usually is a topic to be avoided. But the growing “death café” movement encourages people to discuss their fears and desires about their final moments. VOA’s Jerome Socolovsky reports.
Video

Video Ebola Orphanage Opens in Sierra Leone

Sierra Leone's first Ebola orphanage has opened in the Kailahun district. Hundreds of children orphaned since the beginning of the Ebola outbreak face stigma and rejection with nobody to care for them. Adam Bailes reports for VOA about a new interim care center that's aimed at helping the growing number of children affected by Ebola.
Video

Video Young Nairobi Tech Innovator on 'Track' in Security Business

A 24-year-old technology innovator in Nairobi has invented a tracking device that monitors and secures cars. He has also come up with what he claims is the most robust audio-visual surveillance system yet. As Lenny Ruvaga reports from the Kenyan capital, his innovations are offering alternative security solutions.
Video

Video Latinas Converting to Islam for Identity, Structure

Latinos are one of the fastest growing groups in the Muslim religion. According to the Pew Research Center, about 6 percent of American Muslims are Latino. And a little more than half of new converts are female. VOA’s Carolyn Presutti travelled to Miami, Florida -- where two out of every three residents is Hispanic -- to learn more.
Video

Video Exclusive: American Joins Kurds' Anti-IS Fight

The United States and other Western nations have expressed alarm about their citizens joining Islamic State forces in Syria and Iraq. In a rare counterpoint to the phenomenon, an American has taken up arms with the militants' Syrian Kurdish opponents. Elizabeth Arrott has more in this exclusive profile by VOA Kurdish reporter Zana Omer in Ras al Ayn, Syria.
Video

Video South Korea Confronts Violence Within Military Ranks

Every able-bodied South Korean male between 18 and 35 must serve for 21 to 36 months in the country’s armed forces, depending upon the specific branch. For many, service is a rite of passage to manhood. But there are growing concerns that bullying and violence come along with the tradition. Reporter Jason Strother has more from Seoul.
Video

Video North Carolina Emerges as Key Election Battleground

U.S. congressional midterm elections will be held on November 4th and most political analysts give Republicans an excellent chance to win a majority in the U.S. Senate, which Democrats now control. So what are the issues driving voters in this congressional election year? VOA National Correspondent Jim Malone traveled to North Carolina, one of the most politically competitive states in the country, to find out.
Video

Video Comanche People Maintain Pride in Their Heritage

The Comanche (Indian nation) once were called the “Lords of the Plains,” with an empire that included half the land area of current day Texas, large parts of Oklahoma, New Mexico, Kansas and Colorado.The fierceness and battle prowess of these warriors on horseback delayed the settlement of most of West Texas for four decades. VOA’s Greg Flakus reports from Lawton, Oklahoma, that while their warrior days are over, the 15,000 members of the Comanche Nation remain a proud people.
Video

Video Turkey Campus Attacks Raise Islamic Radicalization Fears

Concerns are growing in Turkey of Islamic radicalization at some universities, after clashes between supporters of the jihadist group Islamic State (IS) or ISIS, and those opposed to the extremists. Pro-jihadist literature is on sale openly on the streets of Istanbul. Critics accuse the government of turning a blind eye to radicalism at home, while Kurds accuse the president of supporting IS - a charge strongly denied. Henry Ridgwell reports from London.

All About America

AppleAndroid