News

Old Medicine May Have New Role in Alzheimer's

Immune globulin shows promise in lab mice

Immune globulin - also called gamma globulin - may help restore the brain's ability to rewire itself.
Immune globulin - also called gamma globulin - may help restore the brain's ability to rewire itself.
Art Chimes

A new study in laboratory animals suggests a promising new avenue for treating Alzheimer's Disease.

The mice in this research were given a medicine that's been around for decades.

Immune globulin - also called gamma globulin - is made from purified blood plasma and is normally used to boost the immune system.

Recently, scientists have been exploring its potential as a treatment for Alzheimer's Disease.

The results of these immune globulin experiments have been inconsistent. Researcher Giulio Maria Pasinetti, of the Mount Sinai School of Medicine in New York, and his colleagues thought these inconsistent results were due to variations in how the immune globulin was administered. So they gave their lab mice very small doses intravenously over four weeks.

Researchers say they saw a dramatic slowdown in the animals' cognitive deterioration.

Pasinetti says the treatment increases certain immune system components called anaphylotoxins, which may help restore plasticity, the ability of the brain to, in effect, rewire itself as needed. It may also have a role in reducing the beta amyloid protein deposits in the brain that are characteristic of Alzheimer's Disease.

The results of Giulio Pasinetti's study were presented at a scientific meeting called Experimental Biology 2012 in San Diego, California.

This forum has been closed.
Comment Sorting
Comments
     
by: PRATIK SHAH
April 27, 2012 8:49 PM
IF THIS TREATMENT CAN GIVE RELIEF TO AD PATIENT WHY AUTHORITY TAKE TOO MUCH TIME TO ANNOUNCE IT ?

Feature Story

FILE - In this June 20, 2014 file photo, immigrants who entered the U.S. illegally stand in line for tickets at the bus station after they were released from a U.S. Customs and Border Protection processing facility in McAllen, Texas.

Mixed Signals on Second Migrant Wave at US Border

The number of Central Americans apprehended at the border peaked in June, but reports from migrants indicate more might be on the way More