News / Health

Researchers Develop Experimental Treatment for Deadly Nipah Virus

FILE - Bats fly over a tree at a central park in Dhaka, Bangladesh, March, 6, 2008.
FILE - Bats fly over a tree at a central park in Dhaka, Bangladesh, March, 6, 2008.
Jessica Berman

Researchers are a step closer to developing a treatment for the deadly Nipah virus, a disease transmitted by fruit bats that has a high mortality rate.  The disease is most common in Asia and South Asia.

Nipah virus causes fever, headache, drowsiness, mental confusion, and left untreated, it can progress to coma. It has a 90 percent mortality rate.  Although rare, it occasionally causes outbreaks among hundreds of people in Malaysia, Singapore, Bangladesh and India through contact with the bodily fluids of infected fruit bats, including their urine.

The highly infectious virus is in the same class as Ebola, Marburg, and Hendra viruses. Currently, there's a serious Ebola outbreak in three countries in western Africa.

Researchers who work with Nipah must wear protective suits, gloves and face masks. Once infected, an individual can spread the illness to other people.

Now, a team of U.S. university and government researchers has discovered an antibody in uninfected individuals that fights the virus. They report their findings this week in Science Translational Medicine.

Lead researcher Thomas Geisbert of the University of Texas Medical Branch says the human monoclonal antibody cured the test animals - African Green Monkeys - even as many as five days after the infection had set in. Otherwise, they would have died within eight to 10 days.

"We give 'em [them] the antibody and they are completely protected against Nipah.  So, that's really a unique aspect and really exciting for us," said Geisbert.

If developed as a therapy for people, that would give public health officials enough time to identify an outbreak and begin treatment.

Geisbert says the antibody is unlike a traditional vaccine, which stimulates the immune system to fight a virus or bacteria.

"The antibody pretty much attacks and targets and blocks the virus from replicating or making more virus particles," said Geisbert.

Because of the deadly nature of Nipah, and the fact that outbreaks occur so infrequently, Geisbert says human safety trials, along with data showing the drug cures sick animals, are enough to gain regulatory approval in the United States.  The process has implications for the development of treatments for other exotic diseases.

Australia, there have been outbreaks of a similar disease called Hendra among race horses.  Health officials there are interested in beginning a safety trial with the Nipah antibody, which is also effective against Hendra, by year's end.

While Nipah is rare, Geisbert says international travel could spread the virus to other countries.   

You May Like

Hezbollah Chief Says Does Not Want War But Ready for One

VOA's Jerusalem correspondent reports that with an Israeli election looming and Hezbollah's involvement in Syria, neither side appears interested in a wider conflict More

Multimedia VOA SPECIAL REPORT: Despite Danger, Best US Minds Battle Deadly Virus

Scientists at America's premier biological research center race in military confinement to find effective drugs, speedier tests and a safe vaccine amid the deadliest outbreak of Ebola in history More

Kurdish Poet Battles to Defend Language, Culture

Kawa Nemir's work is an example of what he sees as an irreversible cultural and political assertiveness among Kurds in Turkey More

This forum has been closed.
Comments
     
There are no comments in this forum. Be first and add one

Featured Videos

Your JavaScript is turned off or you have an old version of Adobe's Flash Player. Get the latest Flash player.
Egypt's Suez Canal Dreams Tempered by Continued Unresti
X
Heather Murdock
January 30, 2015 8:00 PM
Egypt plans to expand the Suez Canal, raising hopes that the end of its economic crisis may be in sight. But some analysts say they expect the project may cost too much and take too long to make life better for everyday Egyptians. VOA's Heather Murdock reports.
Video

Video Egypt's Suez Canal Dreams Tempered by Continued Unrest

Egypt plans to expand the Suez Canal, raising hopes that the end of its economic crisis may be in sight. But some analysts say they expect the project may cost too much and take too long to make life better for everyday Egyptians. VOA's Heather Murdock reports.
Video

Video Threat of Creeping Lava Has Hawaiians on Edge

Residents of the small town of Pahoa on the Big Island of Hawaii face an advancing threat from the Kilauea volcano. Local residents are keeping a watchful eye on creeping lava. Mike O’Sullivan reports.
Video

Video Pro-Kremlin Youth Group Creatively Promotes 'Patriotic' Propaganda

As Russia's President Vladimir Putin faces international pressure over Ukraine and a failing economy, unofficial domestic groups are rallying to his support. One such youth organization, CET, or Network, uses creative multimedia to appeal to Russia's urban youth with patriotic propaganda. VOA's Daniel Schearf reports.
Video

Video Mobile Infrared Scanners May Help Homeowners Save Energy

Mobile photo scanners have been successfully employed for navigational purposes, such as Google Maps. Now, a group of scientists from the Massachusetts Institute of Technology says the same technology could help homeowners better insulate their houses and save some money. VOA’s George Putic has more.
Video

Video Filmmakers Produce Hand-Painted Documentary on Van Gogh

The troubled life of the famous 19th century Dutch painter Vincent van Gogh has been told through many books and films, but never in the way a group of filmmakers now intends to do. "Loving Vincent " will be the first ever feature-length film made of animated hand-painted images, done in the style of the late artist. VOA’s George Putic reports.
Video

Video Issues or Ethnicity? Question Divides Nigeria

As Nigeria goes to the polls next month, many expect the two top presidential contenders to gain much of their support from constituencies organized along ethnic or religious lines. But are faith and regional blocs really what political power in Nigeria is about? Chris Stein reports.
Video

Video Rock-Consuming Organisms Alter Views of Life Processes

Scientists thought they knew much about how life works, until a discovery more than two decades ago challenged conventional beliefs. Scientists found that there are organisms that breathe rocks. And it is only recently that the scientific community is accepting that there are organisms that could get energy out of rocks. Correspondent Elizabeth Lee reports.
Video

Video Paris Attacks Highlight Global Weapons Black Market

As law enforcement officials piece together how the Paris and Belgian terror cells carried out their recent attacks, questions are being asked about how they obtained military grade assault weapons - which are illegal in the European Union. As VOA's Jeff Swicord reports, experts say there is a very active worldwide black market for these weapons, and criminals and terrorists are buying.
Video

Video Activists Accuse China of Targeting Religious Freedom

The U.S.-based Chinese religious rights group ChinaAid says 2014 was the worst year for religious freedom in China since the end of the Cultural Revolution. As Ye Fan reports, activists say Beijing has been tightening religious controls ever since Chinese leader Xi Jinping came to office. Hu Wei narrates.
Video

Video Theologians Cast Doubt on Morality of Drone Strikes

In 2006, stirred by photos of U.S. soldiers mistreating Iraqi prisoners, a group of American faith leaders and academics launched the National Religious Campaign Against Torture. It played an important role in getting Congress to investigate, and the president to ban, torture. VOA's Jerome Socolovsky reports.
Video

Video Former Sudan 'Lost Boy' Becomes Chess Master in NYC

In the mid-1980’s, thousands of Sudanese boys escaped the country's civil war by walking for weeks, then months and finally for more than a year, up to 1,500 kilometers across three countries. The so-called Lost Boys of the Sudan had little time for games. But one of them later mastered the game of chess, and now teaches it to children in the New York area. VOA’s Bernard Shusman in New York has his story.
Video

Video NASA Monitors Earth’s Vital Signs From Space

The U.S. space agency, NASA, is wrapping up its busiest 12-month period in more than a decade, with three missions launched in 2014 and two this month, one in early January and the fifth scheduled for January 29. As VOA’s Rosanne Skirble reports, the instruments being lifted into orbit are focused on Earth’s vital life support systems and how they are responding to a warmer planet.

Circumventing Censorship

An Internet Primer for Healthy Web Habits

As surveillance and censoring technologies advance, so, too, do new tools for your computer or mobile device that help protect your privacy and break through Internet censorship.
More

All About America

AppleAndroid