News / Health

Thailand-US Study Concludes Effectiveness of Daily HIV Medication

Anti-retroviral drug Tenofovir could cut the risk of HIV in half among injected drug users, (File photo).
Anti-retroviral drug Tenofovir could cut the risk of HIV in half among injected drug users, (File photo).
Daniel Schearf
A clinical trial in Thailand has concluded a medication used to treat patients infected with HIV can also act as an effective prevention for all groups at high risk of acquiring the virus that causes AIDS.  The United States-supported study showed the anti-retroviral drug Tenofovir cut the risk of HIV in half among injected drug users, the last high risk group to be tested. 

Researchers from the United States and Thailand said a clinical trial of a medicine to prevent the spread of HIV showed a 49 percent reduction in risk among injected drug users.

Cinical trial

The study of the antiretroviral Tenofovir began in 2005 and involved more than 2,400 men and women who inject drugs but were not infected with HIV.  

Half were given Tenofovir and half a placebo. Both groups received counseling on drug abuse and HIV prevention.  They were then monitored to see how many acquired the virus.

There were 33 HIV infections among those taking the placebo and 17 among those taking the anti-retroviral, a 49 percent reduction in risk.

Trial conclusion

Patients who took the medication most consistently had the highest levels of protection, reducing their risk of infection by 74 percent.

Dr. Michael Martin is chief of HIV research at the U.S. Center for Disease Control and Prevention's Southeast Asia office.  He said while researchers continue to strive for a vaccine that would offer total protection, Tenofovir offers some of the most significant HIV prevention so far.

"We know that it can prevent HIV infection among people who inject drugs, among men who have sex with men, and among heterosexual couples.  So, this is very good news for public health around the world," said Martin.

Trial background

The study was conducted by the U.S. Centers for Disease Control and Prevention in collaboration with the Bangkok Metropolitan Administration and the Thailand Ministry of Public Health.

U.S. Ambassador to Thailand Kristie Kenney hailed the study as another step forward in U.S.-Thailand cooperation to eradicate HIV. "For twenty years Thailand and the United States have collaborated on HIV/AIDS, on the research, on the prevention, with the shared goal of 100 percent HIV/AIDS free generation," he explained. "And, I think today we're taking another important step in that direction."

Tenofovir was approved for use in the United States for HIV treatment in 2001 but was only recently proven effective for prevention.

A 2010 study in the U.S. showed, in combination with another drug, it reduced the risk of HIV infection among men who have sex with men by 44 percent.  Testing in Botswana, Kenya, and Uganda demonstrated effectiveness among heterosexual couples and where one partner was infected with HIV.

Injected drug users were the last high risk group to be tested with Tenofovir in the Bangkok clinical trial.  

Injected drug use accounts for up to 80 percent of new HIV infections in Eastern Europe and Central Asia, eight percent in the United States, and about ten percent worldwide.

Dr. Kachit Choopanya is principal investigator for the study.  He said now that Tenofovir is proven effective for all high risk groups, it is up to governments to bring it into their health care systems. "And, we can save their life…I think everyone, not just Thailand, every country, should do this together," he stated.

An estimated 30 to 50 percent of injected drug users in Thailand are living with HIV.  

Those who participated in the trial reported a decrease in injected drug use, sharing needles, and unprotected sex.  Researchers said that indicates that counseling and education on HIV continues to be one of the most effective forms of prevention.

You May Like

Photogallery Pistorius Sentenced, Taken to Prison

Pistorius, convicted of culpable homicide in shooting death of girlfriend Reeva Steenkamp, will likely serve about 10 months of five-year sentence, before completing it under house arrest More

UN to Aid Central Africa in Polio Vaccinations

Synchronized vaccinations will be conducted after Cameroon reports a fifth case of the wild polio virus in its territory More

WHO: Ebola Vaccine May Be in Use by Jan.

WHO assistant director Dr. Marie Paule Kieny says clinical trials of Ebola vaccines are underway or planned in Europe, US and Africa More

Featured Videos

Your JavaScript is turned off or you have an old version of Adobe's Flash Player. Get the latest Flash player.
After Decades of Pressure, Luxembourg Drops Bank Secrecy Rulesi
X
October 21, 2014 12:20 AM
European Union finance ministers have reached a breakthrough agreement that will make it more difficult for tax cheats to hide their money. The new legislation, which had been blocked for years by countries with a reputation as tax havens, was approved last week after Luxembourg and Austria agreed to lift their vetoes. But as Mil Arcega reports, it doesn’t mean tax cheats have run out of places to keep their money hidden.
Video

Video After Decades of Pressure, Luxembourg Drops Bank Secrecy Rules

European Union finance ministers have reached a breakthrough agreement that will make it more difficult for tax cheats to hide their money. The new legislation, which had been blocked for years by countries with a reputation as tax havens, was approved last week after Luxembourg and Austria agreed to lift their vetoes. But as Mil Arcega reports, it doesn’t mean tax cheats have run out of places to keep their money hidden.
Video

Video Kobani Refugees Welcome, Turkey Criticizes, US Airdrop

Residents of Kobani in northern Syria have welcomed the airdrop of weapons, ammunition and medicine to Kurdish militia who are resisting the seizure of their city by Islamic State militants. The Turkish government, however, has criticized the operation. VOA’s Scott Bobb reports from southeastern Turkey, across the border from Kobani.
Video

Video China Political Meeting Seeks to Improve Rule of Law

China’s communist leaders will host a top level political meeting this week, called the Fourth Plenum, and for the first time in the party’s history, rule of law will be a key item on the agenda. Analysts and Chinese media reports say the meetings could see the approval of long-awaited measures aimed at giving courts more independence and include steps to enhance an already aggressive and high-reaching anti-corruption drive. VOA’s Bill Ide has more from Beijing.
Video

Video US ‘Death Cafes’ Put Focus on the Finale

In contemporary America, death usually is a topic to be avoided. But the growing “death café” movement encourages people to discuss their fears and desires about their final moments. VOA’s Jerome Socolovsky reports.
Video

Video Ebola Orphanage Opens in Sierra Leone

Sierra Leone's first Ebola orphanage has opened in the Kailahun district. Hundreds of children orphaned since the beginning of the Ebola outbreak face stigma and rejection with nobody to care for them. Adam Bailes reports for VOA about a new interim care center that's aimed at helping the growing number of children affected by Ebola.
Video

Video Young Nairobi Tech Innovator on 'Track' in Security Business

A 24-year-old technology innovator in Nairobi has invented a tracking device that monitors and secures cars. He has also come up with what he claims is the most robust audio-visual surveillance system yet. As Lenny Ruvaga reports from the Kenyan capital, his innovations are offering alternative security solutions.
Video

Video Latinas Converting to Islam for Identity, Structure

Latinos are one of the fastest growing groups in the Muslim religion. According to the Pew Research Center, about 6 percent of American Muslims are Latino. And a little more than half of new converts are female. VOA’s Carolyn Presutti travelled to Miami, Florida -- where two out of every three residents is Hispanic -- to learn more.
Video

Video Exclusive: American Joins Kurds' Anti-IS Fight

The United States and other Western nations have expressed alarm about their citizens joining Islamic State forces in Syria and Iraq. In a rare counterpoint to the phenomenon, an American has taken up arms with the militants' Syrian Kurdish opponents. Elizabeth Arrott has more in this exclusive profile by VOA Kurdish reporter Zana Omer in Ras al Ayn, Syria.
Video

Video South Korea Confronts Violence Within Military Ranks

Every able-bodied South Korean male between 18 and 35 must serve for 21 to 36 months in the country’s armed forces, depending upon the specific branch. For many, service is a rite of passage to manhood. But there are growing concerns that bullying and violence come along with the tradition. Reporter Jason Strother has more from Seoul.
Video

Video North Carolina Emerges as Key Election Battleground

U.S. congressional midterm elections will be held on November 4th and most political analysts give Republicans an excellent chance to win a majority in the U.S. Senate, which Democrats now control. So what are the issues driving voters in this congressional election year? VOA National Correspondent Jim Malone traveled to North Carolina, one of the most politically competitive states in the country, to find out.
Video

Video Comanche People Maintain Pride in Their Heritage

The Comanche (Indian nation) once were called the “Lords of the Plains,” with an empire that included half the land area of current day Texas, large parts of Oklahoma, New Mexico, Kansas and Colorado.The fierceness and battle prowess of these warriors on horseback delayed the settlement of most of West Texas for four decades. VOA’s Greg Flakus reports from Lawton, Oklahoma, that while their warrior days are over, the 15,000 members of the Comanche Nation remain a proud people.
Video

Video Turkey Campus Attacks Raise Islamic Radicalization Fears

Concerns are growing in Turkey of Islamic radicalization at some universities, after clashes between supporters of the jihadist group Islamic State (IS) or ISIS, and those opposed to the extremists. Pro-jihadist literature is on sale openly on the streets of Istanbul. Critics accuse the government of turning a blind eye to radicalism at home, while Kurds accuse the president of supporting IS - a charge strongly denied. Henry Ridgwell reports from London.

All About America

AppleAndroid