Urban also won for top album.
Newcomer Gretchen Wilson took home the Top New Artist award and cried when she accepted her second honor as the top Female Vocalist.
Tim McGraw took top single and song honors for his hit "Live Like You Were Dying." He had been nominated in six categories.
Brad Paisley's duet with Alison Krauss on the song "Whiskey Lullaby" won for best video and vocal event.
The country music awards were presented Tuesday night in the western U.S. city of Las Vegas.