The U.S. military says coalition forces killed between 15 to 20 militants in the past two days in Sangin district, of the southern Afghan province of Helmand.
A statement says the militants were carrying assault rifles and grenade launchers.
The violence continued Monday, with two suicide attacks and a roadside bomb blast.
Local officials say a suspected Taleban suicide attacker in a car exploded a bomb near a coalition convoy in Uruzgan province. The attacker died, and one soldier and one civilian were hurt.
Another suicide attacker blew up his car near an Afghan army convoy in Helmand province, killing the attacker but hurting no one else.
Meanwhile, a bomb exploded near a convoy of coalition forces traveling along a highway in southern Kandahar province, injuring two Canadian soldiers.
Violence has intensified in Afghanistan in recent months, as NATO builds up troop numbers in the restive south.Some information for this report was provided by AFP, AP and Reuters.