Brett Myers allowed just two hits over eight innings in his Major League Baseball debut, as the Philadelphia Phillies beat the host Chicago Cubs 4-2 in National League play Wednesday night.
Myers, who struck out five and walked one, outpitched fellow first round pick Mark Prior in a meeting of 21-year-old rookies.
Chicago's Sammy Sosa hit his 31st home run in the loss.
In New York, Brad Wilkerson hit a two run homer to lead the Montreal Expos to a 2-1 win over the host Mets. Vladimir Guerrero threw out the potential trying run at the plate in the seventh inning.
In other National League action:
In the American League, Andy Sheets hit a three-run home run during a six run second inning, as the Tampa Bay Devil Rays posted a 9-5 road victory over the Boston Red Sox.
Boston starter Frank Castillo lasted just one and two-third innings and lost his fifth straight decision.
In Cleveland, Jason Giambi had four hits and drove in three runs, as the New York Yankees beat the host Indians 14-7.
Bernie Williams, Rondell White and Robin Ventura also drove in three runs apiece for the Yankees, who led 10-0 after just two innings.
In other American League action: