People wear masks at a supermarket in Milan, Italy, March 8, 2020.
People wear masks at a supermarket in Milan, Italy, March 8, 2020.

China on Monday reported its lowest number of new coronavirus cases, while about one-quarter of Italy's population was under quarantine orders and passengers from a cruise ship prepared to disembark in the western U.S. state of California after some tested positive for the virus.

Chinese health officials said there were 40 new cases, the lowest there since January just before the government put in place strict restrictions on travel and gatherings in a number of cities.

WATCH: Coronavirus in Italy

Italy began its lockdown in the northern part of the country, including the regions containing the cities of Milan and Venice, Sunday as the death toll spiked by 133 to 366.

Travel into and out the areas will be highly restricted until early next month, as the country seeks to slow the tide of fatalities from the virus. Museums, theaters, cinemas and other entertainment venues have also been ordered to close nationwide.

Italy has also asked retired doctors to return to service to help treat coronavirus victims.

In the United States, there have been 21 deaths from the virus and more than 500 cases reported.

The Grand Princess cruise ship has waited off the coast of California as local and federal officials developed a plan for handling its passengers and crew, some of whom have tested positive for the virus.

Carrying multiple people who have tested positive for COVID-19, the Grand Princess maintains a holding pattern about 30 miles off the coast of San Francisco, March 8, 2020.

It is expected to dock in the city of Oakland on Monday to let the passengers get off.  Those who are California residents will be taken to military facilities in the state to wait out a 14-day quarantine, while residents of other states will be taken to bases in Texas or Georgia.

The U.S. Centers for Disease Control and Prevention said the State Department is working with the home countries of several hundred foreign passengers to arrange getting them home.

The cruise line said the crew will remain on the ship and depart after the passengers leave.

With a confirmed coronavirus case in the area of Indian Wells in southern California that hosts the BNP Paribas Open, tournament officials announced the event will not be held.  It was due to begin this week with a field including such stars as Rafael Nadal, Novak Djokovic, Serena Williams and Naomi Osaka.

Two members of Congress have also said they are self-quarantining after having contact at a recent conference with someone who has tested positive for the coronavirus.

President Donald Trump is denying his administration is giving the public mixed messages.

"We have a perfectly coordinated and fine- tuned plan at the White House for our attack on CoronaVirus. We moved VERY early to close borders to certain areas, which was a Godsend. V.P. is doing a great job. The Fake News Media is doing everything possible to make us look bad. Sad!" Trump wrote on Twitter.

Globally, the World Health Organization said that 100 countries are now reporting coronavirus cases with more than 106,000 people reported as being ill, while deaths have surpassed 3,500.

"While very serious, this should not discourage us," said WHO Director-General Tedros Adhanom Ghebreyesus. "There are many things everyone, everywhere can and should do now."

Tedros praised Italy for "taking bold, courageous steps aimed at slowing the spread of the coronavirus (and) protecting their country. They are making genuine sacrifices." He said the WHO "stands in solidarity" with Italy and "is here to continue supporting you."

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