Malaysia Airlines says an international search is underway for a missing flight from Kuala Lumpur to Beijing carrying 239 passengers and crew.
The airline said it lost all contact with Flight MH370, about two hours after it took off from the Malaysian capital early Saturday morning local time.
At a news conference Saturday, Malaysia Airlines CEO Ahmed Jauhari Yahya said the airline is working with search and rescue teams to locate the aircraft and is calling the families of the passengers and crew.
The company's Facebook page said the passengers represented 14 different nationalities, including 152 Chinese, 38 Malaysians and four Americans.
China's official Xinhua news agency says contact with the Boeing B777-200 was lost in Vietnamese airspace. It says the plane never entered China's air traffic control area. Beijing said it has dispatched at least two rescue vessels to take part in the search.
The most recent accident involving a Boeing 777 was the Asiana Airlines crash at the San Francisco International Airport in July, 2013, in which three people died. Pilot error is suspected in that incident.